Results 11 to 20 of about 16,311 (178)

Pharmacoeconomic evaluation of stroke and myocardial infarction prevention in hypertensive patients: Markov model based on the ACCOMPLISH trial

Journal of International Medical Research, 2023
Objective We evaluated the pharmacoeconomics of amlodipine combined with benazepril and hydrochlorothiazide combined with benazepril in the treatment of hypertension using a Markov model to provide an evidence-based reference for clinical drug use ...
Aozi Feng, Weizhao Lin, Li Li, Mengnan Zeng, Jun Lyu   +4 more
doaj   +1 more source

APROTININ INHIBITED ACUTE PANCREATITIS INDUCED BY HYDROCHLOROTHIAZIDE AND FUROSEMIDE IN EXPERIMENTIAL ANIMALS

Zagazig Journal of Pharmaceutical Sciences, 1997
The effect of the Kallikrein inhibitor, aprotinin, on hydrochlorothiazide and furosemide inducing pancreatitis has been studied in male rats. Treatment of animals with hydrochlorothiazide and furosemide for two weeks significantly increased serum lipase,
Hoda Mohamed , Hazar Yacoub , Salwa El-Melegy , Nadia Gouda   +3 more
doaj   +1 more source

Synthesis of Lanthanium-doped ZnO Nanoflowers: Supported on Graphite Screen Printed Electrode for Selective and Sensitive Detection of Hydrochlorothiazide

International Journal of Electrochemical Science, 2019
In this paper, we report a novel electrochemical sensor for the sensitive detection of hydrochlorothiazide based on La3+/ZnO nanoflower supported on graphite screen printed Electrode.
Rasoul Rezaei, Mohammad Mehdi Foroughi, Hadi Beitollahi, Somayeh Tajik, Shohreh Jahani   +4 more
doaj   +1 more source

Formulation and Characterisation of a Combination Captopril and Hydrochlorothiazide Microparticulate Dosage Form

Pharmaceutics, 2020
Cardiovascular diseases such as hypertension and cardiac failure in South African children and adolescents are effectively managed long term, using a combination treatment of captopril and hydrochlorothiazide.
Mellisa T. R. Chikukwa, Roderick B. Walker, Sandile M. M. Khamanga   +2 more
doaj   +1 more source

Hydrochlorothiazide and risk of hearing disorder: a case series

Journal of Medical Case Reports, 2018
Background Hydrochlorothiazide is not known to cause hearing disorder. The Eritrean Pharmacovigilance Centre, however, has received cases of hearing disorder, including irreversible deafness, associated with hydrochlorothiazide. The aim of this study is,
Natnael Belai, Selamawit Gebrehiwet, Yodit Fitsum, Mulugeta Russom   +3 more
doaj   +1 more source

Bioanalytical method development and validation for determination of metoprolol tartarate and hydrochlorothiazide using HPTLC in human plasma

Brazilian Journal of Pharmaceutical Sciences, 2013
A simple, sensitive, rapid and economic chromatographic method has been developed for determination of metoprolol tartarate and hydrochlorothiazide in human plasma using paracetamol as an internal standard.
Ambadas Ranganath Rote, Poonam Ramdas Sonavane   +1 more
doaj   +1 more source

Validated HPTLC methods for determination of some selected antihypertensive mixtures in their combined dosage forms

Bulletin of Faculty of Pharmacy Cairo University, 2014
Simple and selective HPTLC methods were developed for the simultaneous determination of the antihypertensive drugs; carvedilol and hydrochlorothiazide in their binary mixture (Mixture I) and amlodipine besylate, valsartan, and hydrochlorothiazide in ...
Rasha A. Shaalan, Tarek S. Belal, Fawzy A. El Yazbi, Sohila M. Elonsy   +3 more
doaj   +1 more source

Comparative effects of valsartan plus cilnidipine or hydrochlorothiazide on nocturnal home blood pressure

The Journal of Clinical Hypertension, 2021
We tested our hypothesis that, in hypertensive patients with higher nocturnal home systolic blood pressure (HSBP) at baseline, a valsartan/cilnidipine (80/10 mg) combination would reduce nocturnal HSBP more markedly than a valsartan/hydrochlorothiazide ...
Takeshi Fujiwara, Satoshi Hoshide, Naoko Tomitani, Hiroshi Kanegae, Kazuomi Kario   +4 more
doaj   +1 more source

Evaluation and Comparison of Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) as Vectors to Develop Hydrochlorothiazide Effective and Safe Pediatric Oral Liquid Formulations

Pharmaceutics, 2021
The aim of this study was the optimization of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in terms of physicochemical and biopharmaceutical properties, to develop effective and stable aqueous liquid formulations of ...
Paola Mura, Francesca Maestrelli, Mario D’Ambrosio, Cristina Luceri, Marzia Cirri   +4 more
doaj   +1 more source

Interaction and Compatibility Studies in the Development of Olmesartan Medoxomil and Hydrochlorothiazide Formulations under a Real Manufacturing Process

Pharmaceutics, 2022
A drug–drug and drug–excipient interactions and compatibilities study was conducted for two fixed-dose combination (FDC) products containing olmesartan medoxomil (OLM)/hydrochlorothiazide (HCT) 20/12.5 mg and OLM/HCT 40/12.5 mg during their development ...
Mac Arturo Murillo-Fernández, Ernesto Montero-Zeledón, Ariadna Abdala-Saiz, José Roberto Vega-Baudrit, Andrea Mariela Araya-Sibaja   +4 more
doaj   +1 more source