Results 101 to 110 of about 113,315 (298)

Hydrocortisone as an Intervention for Dexamethasone-Induced Adverse Effects in Pediatric Patients With Acute Lymphoblastic Leukemia: Results of a Double-Blind, Randomized Controlled Trial.

Journal of Clinical Oncology, 2016
PURPOSE Dexamethasone is a key component in the treatment of pediatric acute lymphoblastic leukemia (ALL), but can induce serious adverse effects. Recent studies have led to the hypothesis that neuropsychological adverse effects may be a result of ...
Lidewij T Warris, M. M. van den Heuvel-Eibrink, F. Aarsen, S. Pluijm, M. Bierings, C. van den Bos, C. Zwaan, H. Thygesen, W. Tissing, M. Veening, R. Pieters, E. L. van den Akker   +11 more
semanticscholar   +1 more source

The Bioengineering of Microspheric Skin Organoids and Their Application in Drug Screening

Advanced Science, EarlyView.
A novel method for the preparation of uniform microspheric skin organoids via spinning bioreactors is developed. The organoid consists of a core‐shell structure to mimic the bilayered skin structure with the epidermis on the surface. For efficient drug screening, the organoid is equipped with a luciferase reporter to detect canonical Wnt signaling, and
Jundong Xie, Qingyang Yang, Yanan Zhang, Ke Zheng, Hongya Geng, Yaojiong Wu   +5 more
wiley   +1 more source

General theory of inflammation: patient self-administration of hydrocortisone safely achieves superior control of hydrocortisone-responding disorders by matching dosage with symptom intensity

Journal of Inflammation Research, 2019
John B Irwin,1 AL Baldwin,2 Virgil I Stenberg31Private Practice, Tarrington, CT, USA; 2Department of Physiology, School of Medicine, University of Arizona School of Medicine, Tucson, AZ, USA; 3University of North Dakota, Grand Forks, ND, USA†John ...
Irwin JB, Baldwin AL, Stenberg VI
doaj  

Studies on human synovial membrane in vitro. The metabolism of normal and rheumatoid synovia and the effect of hydrocortisone [PDF]

, 1958
D. P. Page Thomas, J. T. Dingle
openalex   +1 more source

A Touch Enabled Hemodynamic and Metabolic Monitor

Advanced Science, EarlyView.
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi, Tamoghna Saha, Ponnusamy Nandhakumar, Muhammad Inam Khan, Hannah Fishman, Sara Earney, Chochanon Moonla, Yuchen Xu, Henry Thai, Sofia Morales‐Fermin, Gyeongho Kim, Rhea Park, Beya Acot, Oscar Wu, Cannon Wurster, An‐Yi Chang, Christopher Cheung, Julia Silberman, Shichao Ding, Joseph Wang   +19 more
wiley   +1 more source

Local Injection of Hydrocortisone and Procaine in Osteo-Arthritis of the Hip Joint [PDF]

, 1956
V. M. Leveaux, Caroline Quin
openalex   +1 more source

Effects of Hydrocortisone on the Regulation of Blood Pressure: Results From a Randomized Controlled Trial.

Journal of Clinical Endocrinology and Metabolism, 2016
CONTEXT Cardiovascular risk is increased in patients with secondary adrenal insufficiency, which may be ascribed to an unfavorable metabolic profile consequent to a relatively high hydrocortisone replacement dose. OBJECTIVE We determined the effects of
Jorien Werumeus Buning, M. van Faassen, Pauline Brummelman, R. Dullaart, G. van den Berg, M. M. van der Klauw, M. Kerstens, C. Stegeman, A. M. Muller Kobold, I. Kema, B. Wolffenbuttel, A. V. van Beek   +11 more
semanticscholar   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

Ocular Pharmacological Profile of Hydrocortisone in Dry Eye Disease

Frontiers in Pharmacology, 2019
To investigate the ocular pharmacological profile of hydrocortisone (HC) using in vitro and in vivo models of dry eye disease. Rabbit corneal epithelial cells (SIRCs) were used to assess the effect of HC in two paradigms of corneal damage: hyperosmotic ...
Claudio Bucolo, Claudio Bucolo, Annamaria Fidilio, Claudia Giuseppina Fresta, Francesca Lazzara, Chiara Bianca Maria Platania, Giuseppina Cantarella, Giulia Di Benedetto, Chiara Burgaletto, Renato Bernardini, Cateno Piazza, Stefano Barabino, Filippo Drago, Filippo Drago   +13 more
doaj   +1 more source

A phase 2 study of Chronocort, a modified-release formulation of hydrocortisone, in the treatment of adults with classic congenital adrenal hyperplasia.

Journal of Clinical Endocrinology and Metabolism, 2015
CONTEXT Treatment of congenital adrenal hyperplasia (CAH) is suboptimal. Inadequate suppression of androgens and glucocorticoid excess are common and current glucocorticoid formulations cannot replace the cortisol circadian rhythm.
A. Mallappa, N. Sinaii, Parag Kumar, M. Whitaker, L. Daley, Dena Digweed, D. Eckland, C. Van Ryzin, L. Nieman, W. Arlt, R. Ross, D. Merke   +11 more
semanticscholar   +1 more source