Results 101 to 110 of about 175,705 (335)

Effects of Systemically Administered Hydrocortisone on the Human Immunome

Scientific Reports, 2016
Corticosteroids have been used for decades to modulate inflammation therapeutically, yet there is a paucity of data on their effects in humans. We examined the changes in cellular and molecular immune system parameters, or “immunome”, in healthy humans ...
M. Olnes, Yuri Kotliarov, A. Biancotto, Foo Cheung, Jinguo Chen, R. Shi, Huizhi Zhou, E. Wang, J. Tsang, R. Nussenblatt, Howard B. Christopher S. Francesco M. J. Phillip Shira Pa Dickler Hourigan Marincola McCoy Perl Schum Schwar, H. Dickler, C. Hourigan, F. Marincola, J. P. Mccoy, S. Perl, Paula Schum, P. Schwartzberg, G. Trinchieri, Janet Valdez, N. Young   +20 more
semanticscholar   +1 more source

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

Advanced Healthcare Materials, EarlyView.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer, Arundhati Joshi, Constantin von Kaisenberg, Dorothea Brüggemann, Cornelia Lee‐Thedieck   +4 more
wiley   +1 more source

Formulation of Carbopol®/Poly(2-ethyl-2-oxazoline)s Mucoadhesive Tablets for Buccal Delivery of Hydrocortisone

Polymers, 2018
Poly(2-ethyl-2-oxazoline) has become an excellent alternative to the use of poly(ethylene glycol) in pharmaceutical formulations due to its valuable physicochemical and biological properties. This work presents a formulation of poorly-water soluble drug,
L. Ruiz‐Rubio, M. L. Alonso, L. Pérez-Álvarez, R. Alonso, J. Vilas, V. Khutoryanskiy   +5 more
semanticscholar   +1 more source

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source

Hydrocortisone treatment is associated with early recovery from severe septic shock in patients with obstructive pyelonephritis due to upper urinary tract stone

BJUI Compass
Objectives The administration of hydrocortisone in patients with severe septic shock contributes to early recovery in intensive care. The purpose of this study was to evaluate the effect of hydrocortisone on early recovery from severe septic shock in ...
Isamu Otsuka, Koshiro Nishimoto, Taichi Kozako, Katsuhiro Kanemaru, Yasuhiro Yamashita, Toshiyuki Kamoto, Atsuro Sawada   +6 more
doaj   +1 more source

Rationale for Prolonged Glucocorticoid Use in Pediatric ARDS: What the Adults Can Teach Us. [PDF]

, 2016
Based on molecular mechanisms and physiologic data, a strong association has been established between dysregulated systemic inflammation and progression of acute respiratory distress syndrome (ARDS).
Meduri, Gianfranco Umberto, Schwingshackl, Andreas   +1 more
core   +1 more source

4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa, Alessio Esposito, Giovanni Vozzi, Riccardo Gottardi, Carmelo De Maria   +4 more
wiley   +1 more source

Antiemetic efficacy of high-dose hydrocortisone in patients receiving cisplatin therapy [PDF]

, 1986
Cisplatin療法にhydrocortisone succinateを使用し, 消化器合併症を4段階評価で査定した.1) Cisplatin 7～20 mg/m2/日×5日間を中心とする多剤併用療法にhydrocortisone 900～1, 800 mg/日を使用した場合, 嘔気, 嘔吐回数, 食欲不振の症状は有意に軽減した.2) Cisplatin 30～40 mg/m2/日×1日を中心とする多剤併用療法では, hydrocortisone 1, 500～2, 400 mgの使用は ...
坂田, 安之輔, 小松原, 秀一, 峰山, 浩忠, 渡辺, 学, 阿部, 禮男   +4 more
core  

Adjunctive Glucocorticoid Therapy in Patients with Septic Shock. [PDF]

, 2018
Background Whether hydrocortisone reduces mortality among patients with septic shock is unclear. Methods We randomly assigned patients with septic shock who were undergoing mechanical ventilation to receive hydrocortisone (at a dose of 200 mg per day) or
Anders Perner, Andrew Rhodes, Annane D, Balasubramanian Venkatesh, Billot L, Christopher Joyce, Colin McArthur, Dorrilyn Rajbhandari, Holm S, Jeremy Cohen, John Myburgh, Kelly Thompson, Laurent Billot, Maryam Correa, Meg Harward, Parisa Glass, Qiang Li, Rinaldo Bellomo, Simon Finfer, Steve Webb, Venkatesh B, Venkatesh B, Yaseen Arabi   +22 more
core   +1 more source

Bioelectronic Sensors for Neuromuscular Perception in Human‐Machine Interfaces

Advanced Robotics Research, EarlyView.
This review summarizes recent advances in bioelectronic sensors for neuromuscular perception in human‐machine interfaces. By integrating biopotential, electrical impedance, and electrochemical sensing strategies with flexible electrode interfaces, these bioelectronic sensing systems enable intuitive, real‐time detection of muscle and nerve activity ...
Junwei Li, Bangyan Niu, Kunlin Wu, Jingcheng Xiao, Xiaoyan Liu, Yifan Wang   +5 more
wiley   +1 more source