Results 111 to 120 of about 175,705 (335)

Analysis of common oral and topical dermatologic medication price variation by source [PDF]

open access: yes, 2020
Online coupon retailers and pharmacies are popular sites that patients can access discounted medications when compared to cash prices. These sources are especially important for those patients without insurance.
Boyko, Alexander, Smith, Gideon P
core  

Activity of different desoximetasone preparations compared to other topical corticosteroids in the vasoconstriction assay [PDF]

open access: yes, 2008
Introduction: We report on a double-blind, vehicle-controlled, single-center confirmatory study with random assignment. The purpose of the study was to investigate the topical bioavailability of different topical corticosteroid formulations in healthy ...
Ashton RE   +17 more
core   +1 more source

Temperature‐Dependent Stability of Components in a Particle‐based Continuous Biosensor

open access: yesAdvanced Sensor Research, EarlyView.
The temperature‐dependent stability was studied of components in a continuous biosensor based on particle motion. The particles and surface of a competitive immuno‐sensor for small‐molecule monitoring were separately aged and their functionalities quantified. The results give pointers on how long‐term changes of continuous affinity‐based biosensors can
Sebastian Cajigas   +3 more
wiley   +1 more source

Effect of a combination of 0.001% hydrocortisone and 0.2% hyaluronic acid on conjunctival cytology in patients with dysregulatory inflammatory changes of the conjunctiva in type 2 diabetes

open access: yesJournal of Ophthalmology
Purpose. To assess and evaluate cytological changes of conjunctival epithelial cells collected by CIC and relative expression of CD15 before and after 2-month treatment with sodium hyaluronate 0.2% and 0.001% hydrocortisone among patients with ...
T. Zhmud, S. Barabino, G. Drozhzhyna
doaj   +1 more source

An oral multiparticulate, modified-release, hydrocortisone replacement therapy that provides physiological cortisol exposure [PDF]

open access: yes, 2014
Objective It is not possible with current hydrocortisone replacement to mimic the diurnal cortisol profile in patients with adrenal insufficiency. Previous attempts with modified-release technology were unsuccessful.
Arlt   +23 more
core   +1 more source

A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors

open access: yesAdvanced Science, EarlyView.
A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu   +12 more
wiley   +1 more source

Development of a Hydrocortisone Orodispersible Thin Film Containing Its Succinate Prodrug

open access: yesPharmaceuticals
Orodispersible thin film (ODF) is an innovative dosage form that allows for adjustable dosing and improved patient compliance. It is administered by mouth, where it dissolves, making it suitable for children.
Clément Boisseillier   +9 more
doaj   +1 more source

Concomitant arginine-vasopressin and hydrocortisone therapy in severe septic shock: association with mortality [PDF]

open access: yes, 2018
Purpose: To evaluate the association between concomitant arginine-vasopressin (AVP)/hydrocortisone therapy and mortality in severe septic shock patients.
Dünser, Martin   +6 more
core  

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

open access: yesAdvanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang   +12 more
wiley   +1 more source

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