Results 121 to 130 of about 175,705 (335)
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu +9 more
wiley +1 more source
Role of very short-term intravenous hydrocortisone in reducing postdural puncture headache
Objective: Headache is not an uncommon complication of spinal anesthesia. The efficacy of intravenous (IV) hydrocortisone in treating the patients with postdural puncture headache was observed in this study.
Md Rabiul Alam +2 more
doaj +1 more source
Incidence and treatment of rejection episodes in primary orthotopic liver transplantation under FK 506. [PDF]
FK 506 therapy with low doses of steroids was adequate to control rejection in most liver recipients. Rejection episodes were readily reversed with single IV doses of methylprednisone or hydrocortisone.
Abu-Elmagd, K +7 more
core
Differential effects of steroids and retinoids on bovine myelopoiesis in vitro [PDF]
Pregnancy and parturition are associated with physiological changes caused by steroid hormones. Alterations in number, maturity, and function of polymorphonuclear leukocytes observed in dairy cows at parturition suggest a common causative relationship ...
Burvenich, Christian +3 more
core +1 more source
A matrix‐free human liver organoid–T cell co‐culture platform enables modeling of immune‐mediated drug‐induced liver injury (iDILI). Using flucloxacillin and patient‐matched cells, this system recapitulates HLA‐B*57:01–restricted CD8⁺ T cell activation and hepatocyte damage.
Fadoua El Abdellaoui Soussi +11 more
wiley +1 more source
Role of hydrocortisone in prevention of pain on propofol injection
Background and Objectives : Pain following intravenous injection of propofol continues to be an intriguing problem. None of the commonly used methods completely attenuate the pain. Inflammatory response to propofol contributes to the pain.
Monu Yadav, Padmaja Durga, R Gopinath
doaj +1 more source
Glucocorticoid receptor signalling activates YAP in breast cancer [PDF]
The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo pathway leads to aberrant activation of the transcription co-activator YAP ...
Bertolio, Rebecca +12 more
core +3 more sources
Quality of compounded hydrocortisone capsules used in the treatment of children.
OBJECTIVES Due to the lack of paediatric-licensed formulations, children are often treated with individualized pharmacy-compounded adult medication. An international web-based survey about the types of medication in children with adrenal insufficiency ...
U. Neumann +6 more
semanticscholar +1 more source
Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li +18 more
wiley +1 more source

