Results 121 to 130 of about 87,509 (230)

Human coronary artery organ‐chip with circulating immune cells recapitulates anti‐inflammatory effect of pulsatile wall strain

Interdisciplinary Medicine, EarlyView.
A fully characterised organ‐on‐a‐chip model of the human coronary artery with endothelial and smooth muscle cells, plus circulating immune cells, created on the Emulate platform. The model successfully recapitulates the physiological effects of pulsatile vessel dilation on cell morphology and the localised inflammatory susceptibility to TNF‐α ...
Yu Hou, Georgios Ziakas, Tim Hopkins, Wen Wang, Hazel R. C. Screen, Martin M. Knight   +5 more
wiley   +1 more source

Correction: Hydrocortisone combined with fludrocortisone for treatment of adults with septic shock: an updated meta-analysis and systematic review. [PDF]

Front Med (Lausanne)
Sun A, Gao X, Gao Z, Zhang Q, He W.
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Hydrocortisone in Preterm Infants and School-Age Functional Outcomes: Follow-Up of a Randomized Clinical Trial. [PDF]

JAMA Pediatr
DeMauro SB, Kirpalani H, Hintz S, Watterberg KL, Watson V, Lowe J, Shankaran S, Chawla S, Vohr B, Msall ME, D'Angio CT, Yoder BA, Lai K, Winter S, Colaizy TT, Merhar SL, Ziolkowski K, Bann CM, Trotta M, Newman JE, Walsh MC, Higgins RD, Cahill TE, Duncan AF, Wilson-Costello DE, Peralta-Carcelen M, Arnold H, Mosquera RA, Heyne RJ, Fuller J, McGowan EC, Cavanaugh B, Harmon HM, Maitre NL, Neel ML, Van Meurs KP, Richards LA, Kilbride HW, Hines AC, Natarajan G, Trembath A, Benninger KL, Kesavan K, Malcolm WF, Zanger D, Reynolds AM, Carlson M, Das A, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.   +48 more
europepmc   +1 more source

Impact of Childhood Family Conflict on Adolescents' Startle Reactivity to Threat: The Moderating Role of Sensory Processing Sensitivity

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Chronic familial conflict is known to hinder the development of adaptive stress responding in adolescents. However, there are differences in how individuals respond to familial conflict, which may be explained by the temperament trait of Sensory Processing Sensitivity (SPS).
Sophia A. Bibb, Kathryn C. Jenkins, Alexa House, Kayla A. Kreutzer, K. Luan Phan, Stephanie M. Gorka   +5 more
wiley   +1 more source

Continuous subcutaneous hydrocortisone infusion in pediatric primary adrenal insufficiency: a cohort study. [PDF]

Endocr Connect
Fouatih K, Trouvin MA, Lambert AS, Rothenbuhler A, Verdelet T, Lecoq AL, Bouligand J, Laddada L, Chappell K, Lopez M, Bouyacoub M, Yahia A, Haidar H, Trabado S, Linglart A, Bouvattier C, Ait Tayeb AEK.   +16 more
europepmc   +1 more source

Pawsitive Connections: Understanding How Informal Pet Interactions Relate to Daily Youth Functioning

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Human‐animal interaction (HAI) has been linked to well‐being across functional domains and throughout the lifespan. Limited research has explored specific types of informal HAIs with pets or the impact of HAI in daily life. Methods Over 2 weeks in 2021, caregivers of youth (N = 42; ages 6–17, M = 12.21; 50% male) reported daily on
Tanya Mitropoulos, Shelby McDonald, Charles Calderwood, Rosanna Breaux   +3 more
wiley   +1 more source

A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome. [PDF]

Pharmaceuticals (Basel)
Boshra MS, Ezzat M, Ibrahim M, Alsheikh MY, Hussein RRS, Kamal M.   +5 more
europepmc   +1 more source

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin, Heloisa Amancio, Jessica Zablocki da Luz, Aliciane de Almeida Roque, Tugstênio Lima de Souza, José Eduardo Vargas, Ciro Alberto de Oliveira Ribeiro, Francisco Filipak Neto   +7 more
wiley   +1 more source

Impact of Intravenous Hydrocortisone on Postoperative Atrial Fibrillation and Outcomes in Patients Receiving Vasopressor Support Following On-Pump Coronary Artery Bypass Grafting. [PDF]

Hosp Pharm
Paytes E, Mefford B, Love B, Amick A, Cox J.   +4 more
europepmc   +1 more source