Results 141 to 150 of about 132,529 (339)
Advanced Science, EarlyView.Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou +15 more
wiley +1 more source
Advanced Science, EarlyView.Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen +24 more
wiley +1 more source
ON THE RATE OF HYDROCORTISONE CLEARANCE FROM PLASMA IN PREGNANT WOMEN AND IN PATIENTS WITH LAENNEC'S CIRRHOSIS* [PDF]
, 1959 Nicholas P. Christy +3 more
openalex +1 more source
Advances in Medical Devices for Augmented Acupuncture Therapy
Advanced Science, EarlyView.Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai +7 more
wiley +1 more source
Advanced Science, EarlyView.Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas +16 more
wiley +1 more source
Bronchial Asthma and Chronic Bronchitis Treated with Hydrocortisone Acetate Inhalations [PDF]
, 1958 W. H. Helm, F Heyworth
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Magnetically Controllable and Degradable Milliscale Swimmers as Intraocular Drug Implants
Advanced Science, EarlyView.Magnetically controllable degradable milliscale swimmers (MDMS) offer a promising alternative to commercial intraocular drug implants, reducing complications like implant dislocation and uncontrolled drug release. MDMS achieve high velocities in ocular environments, enable real‐time imaging, and deliver drugs effectively without disrupting retinal ...
Erdost Yildiz +8 more
wiley +1 more source
Comparative Efficacy of Dexamethasone versus Hydrocortisone in Severe Acute Pediatric Asthma
Iranian Journal of Allergy, Asthma and Immunology, 2007 This study aimed to compare the efficacy of dexamethasone and hydrocortisone in the treatment of acute paediatric asthma. Forty seven asthmatic children were randomised to receive either dexamethasone (0.6 mg/ml, maximum 16 mg) in a single dose or ...
Sedigheh Ebrahimi Bahador Sarkari
doaj
The Penetration and Distribution of C14-Hydrocortisone in Human Skin After Its Topical Application1
, 1956 Allene Scott, Frederick Kalz
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