Results 81 to 90 of about 24,495 (263)

Glucose Deprivation‐Driven Concurrent Induction of Apoptosis/Disulfidptosis/Ferroptosis by Tumor Targeting Nanoassemblies in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Innovative hybrid nanoassemblies installed with ferrocene, D‐α‐tocopherol succinate, and phloretin exploit the metabolic vulnerability of triple‐negative breast cancer under glucose starvation. By blocking glucose uptake, this single nanoplatform simultaneously orchestrates apoptosis, disulfidptosis, and ferroptosis to achieve synergistic and ...
Song Yi Lee, ChaeRim Hwang, Seong Eun Kim, Mrinmoy Karmakar, Seo Jin Jung, Hyeonseok Jang, Hae‐In Kim, Heejung Yang, Junmin Lee, Dae‐Duk Kim, Hyun‐Jong Cho   +10 more
wiley   +1 more source

jetsimpy: A Highly Efficient Hydrodynamic Code for Gamma-Ray Burst Afterglow

The Astrophysical Journal Supplement Series
Gamma-ray burst (GRB) afterglows are emissions from ultrarelativistic blast waves produced by a narrow jet interacting with surrounding matter. Since the first multimessenger observation of a neutron star merger, hydrodynamic modeling of GRB afterglows ...
Hao Wang, Ranadeep G. Dastidar, Dimitrios Giannios, Paul C. Duffell   +3 more
doaj   +1 more source

Synthesis of AgBiS2 and AgInS2 Based on Formation Energies in Sulfur‐Rich Reducing Flame

Advanced Functional Materials, EarlyView.
High‐surface‐area AgInS2 and AgBiS2 nanoparticles were synthesized via enclosed flame spray pyrolysis by tuning flame conditions and formation energies to guide phase formation. Flame parameters were tuned to suppress oxides and enable pure sulfide phase growth.
Muhammad Ali Martuza, Marco Schowalter, Andreas Rosenauer, Olga V. Kuharenko, Christian Rossner, Johannes Birkenstock, Lutz Mädler, Suman Pokhrel   +7 more
wiley   +1 more source

Bottomonium transport in a strongly coupled quark-gluon plasma

Physics Letters B
Quarkonium production in high-energy heavy-ion collisions remains a key probe of the quark-gluon plasma formed in these reactions, but the development of a fully integrated nonperturbative approach remains a challenge.
Biaogang Wu, Ralf Rapp
doaj   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Kinematic and dynamical origins of mean-pT fluctuations in heavy-ion collisions

Physics Letters B
Event-by-event fluctuations of the mean transverse momentum (mean-pT) provide a sensitive probe of collective dynamics beyond single-particle spectra and anisotropic flow.
Lipei Du
doaj   +1 more source

Fructose‐Based Single‐Chain Polymer Nanoparticles for GLUT1–Mediated Delivery: Impact of Polymer Design on Uptake and In Vivo Performance

Advanced Healthcare Materials, EarlyView.
Single‐chain nanoparticles have been proposed as drug delivery carriers, but adding a tail can significantly enhance their performance. This was demonstrated using a tadpole‐like structure comprising a head prepared from a UV‐crosslinked fructose‐based glycopolymer capable of targeting GLUT receptors, combined with a PEG‐based tail. Compared with other
Hoang Yen Vo, Linqing Tian, Qiaoyun Wang, Evelyn Szabo, Rebecca Y. Lai, Fariba Dehghani, Martina H. Stenzel   +6 more
wiley   +1 more source

Universal density shift coefficients for the thermal conductivity and shear viscosity of a unitary Fermi gas

Physical Review Research
We measure universal temperature-independent density shifts for the thermal conductivity κ_{T} and shear viscosity η, relative to the high temperature limits, for a normal phase unitary Fermi gas confined in a box potential. We show that a time-dependent
Xiang Li, J. Huang, J. E. Thomas
doaj   +1 more source

Development of a novel storm surge inundation model framework for efficient prediction [PDF]

Geoscientific Model Development
Storm surge is a natural process that causes flood disasters in coastal zones and results in massive casualties and property losses. Therefore, storm surge inundation is of major concern in formulating appropriate strategies for disaster prevention and ...
X. Gao, X. Gao, S. Li, S. Li, S. Li, S. Li, D. Mo, D. Mo, D. Mo, D. Mo, Y. Liu, Y. Liu, Y. Liu, Y. Liu, P. Hu, P. Hu, P. Hu, P. Hu   +17 more
doaj   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

Advanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He, Nicholas L. Fletcher, Gayathri R. Ediriweera, Yifei Zhu, James Humphries, Christopher B. Howard, Jiazheng Wang, Craig A. Bell, Kristian Kempe, Kristofer J. Thurecht   +9 more
wiley   +1 more source