Results 251 to 260 of about 1,809,603 (303)

Supramolecular Chiral Assemblies from Benzoselenadiazole‐Alanine‐Acylhydrazone Conjugates Enable Cardioprotection

Advanced Science, EarlyView.
The C3‐symmetric conjugate TASe, which integrates benzoselenadiazole, alanine, and acylhydrazone modules, self‐assembles into a chalcogen‐/hydrogen‐bonded porous framework in the solid state and uniform chiral nanospheres in aqueous media. These assemblies protect cardiomyocytes from doxorubicin‐induced oxidative injury by scavenging intracellular ...
Jinkui Teng, Renjing Yang, Yu Du, Jingzhong Duan, Yiming Xu, Zhihua He, Guanghui Wang, Wenjing Tian, Aijie Liu, Haifeng Chen, Yun‐Bao Jiang, Xiaosheng Yan   +11 more
wiley   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Microbial community dynamics during historic drought and flood in Great Salt Lake. [PDF]

Appl Environ Microbiol
Phillips APR, Lee AE, Mortensen B, Martinez-Koury P, Izadifar S, Dutta S, Baxter BK, Schmid AK.   +7 more
europepmc   +1 more source

Topological Quantum Biomaterials Enable Pyroptosis‐Senescence Coupling for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
This work reports conceptually unprecedented topological quantum biomaterials derived from engineered Pd3Sn nanostrips for oncological applications. Their near‐Fermi‐level electronic architecture and superior interfacial charge transport facilitate ultrasound‐amplified redox reactions and efficient ROS generation.
Zilu Chen, Kun Mei, Yan Yang, Mengna Xu, Xinyue Dai, Renjun Gu, Fuqiong Zhou, Cheng Wang, Meiqi Chang, Yan Huang, Yu Chen   +10 more
wiley   +1 more source

Efficient formation of a massive quiescent galaxy at redshift 4.9. [PDF]

Nat Astron
de Graaff A, Setton DJ, Brammer G, Cutler S, Suess KA, Labbé I, Leja J, Weibel A, Maseda MV, Whitaker KE, Bezanson R, Boogaard LA, Cleri NJ, De Lucia G, Franx M, Greene JE, Hirschmann M, Matthee J, McConachie I, Naidu RP, Oesch PA, Price SH, Rix HW, Valentino F, Wang B, Williams CC.   +25 more
europepmc   +1 more source

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

Advanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing, Ziyi Zhao, Yuhui Yang, Yichen Lin, Yinglin Xuan, Ziyang Wang, Kai Lv, Xiaoxu Zhu, Zhi Zhang, Dong Ma   +9 more
wiley   +1 more source

Energy dependence of the deformed nuclear structure at small-<i>x</i>. [PDF]

Eur Phys J C Part Fields
Mäntysaari H, Singh P.
europepmc   +1 more source

Turbulent mixing controls fixation of growing antagonistic populations. [PDF]

Proc Natl Acad Sci U S A
Bauermann J, Benzi R, Nelson DR, Shankar S, Toschi F.   +4 more
europepmc   +1 more source

Neuronal Synchronization and Bidirectional Activity Spread Explain Efficient Swimming in a Whole-Body Model of Hydrozoan Jellyfish. [PDF]

J Neurosci
Pallasdies F, Norton P, Schleimer JH, Schreiber S.   +3 more
europepmc   +1 more source

Effects of inbound attendees of a mass gathering event on the COVID-19 epidemic using individual-based simulations. [PDF]

PLoS One
Saito MM, Katayama K, Naruse A, Ruan P, Murakami M, Okuda T, Ysutaka T, Naito W, Tsubokura M, Imoto S.   +9 more
europepmc   +1 more source