Results 101 to 110 of about 184,106 (366)

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano   +11 more
wiley   +1 more source

Finite-element modeling of liquid-crystal hydrodynamics with a variable degree of order [PDF]

open access: yes, 2006
A finite-element model of liquid-crystal hydrodynamics based on the Qian and Sheng formulation has been developed. This formulation is a generalization of the Ericksen-Leslie theory to include variations in the order parameter, allowing for a proper ...
Richard James   +7 more
core  

Visualization of Elongation Measurements Using an Ser Universal Testing Platform

open access: yesApplied Rheology, 2015
A Sentmanat Extension Rheometer represents one out of a few experimental devices for the measurement of elongational viscosity of polymer melts. However, the appropriateness of this technique for individual polymer materials is not sufficiently apparent ...
Pivokonsky R., Filip P., Zelenkova J.
doaj   +1 more source

Engineering Nanoplatforms for Alzheimer's Disease Detection via Biomolecular Corona Proteomic and Lipidomic Profiling

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered nanoparticles capture disease‐specific biomolecular coronas that uncover hidden molecular features of Alzheimer's disease. Combined proteomic and lipidomic analyses reveal a characteristic shift in ribosomal machinery and energy metabolism, generating a multiomic fingerprint that supports accurate disease detection and opens new ...
Antonietta Greco   +7 more
wiley   +1 more source

A Numerical Study of Fluid Flow in a Vertical Slot Fishway with the Smoothed Particle Hydrodynamics Method [PDF]

open access: yes, 2019
Fishways have a great ecological importance as they help mitigate the interruptions of fish migration routes. In the present work, the novel DualSPHysics v4.4 solver, based on the smoothed particle hydrodynamics method (SPH), has been applied to perform ...
Angelantonio Tafuni   +9 more
core   +1 more source

Macrophage Membrane‐Camouflaged Nanozyme Microneedles Restore Immunovascular Homeostasis Through SPP1‐ApoE Signaling in Diabetic Wounds

open access: yesAdvanced Healthcare Materials, EarlyView.
Macrophage membrane‐coated Cu/Zn‐MOF nanozyme microneedles (MNs) reprogram the diabetic wound microenvironment through localized, minimally invasive delivery. By suppressing M1‐like macrophage activation while promoting extracellular matrix deposition and angiogenesis, this biomimetic platform accelerates diabetic wound repair.
Qipeng Wu   +7 more
wiley   +1 more source

Hydrodynamics of high gas-liquid ratio flows in a rotor-stator spinning disc reactor [PDF]

open access: yes, 2015
The rotor-stator Spinning Disc Reactor (rs-SDR) is a versatile continuous flow reactor aiming at intensification of (micro)mixing and intensification of mass and heat transfer rates for both single and multiphase processes [e.g. 1,2].
Schaaf, van der, J.   +3 more
core  

Impaction bone grafting for acetabular bone defects replacement in revision hip arthroplasty: biomechanical aspects [PDF]

open access: yesTravmatologiâ i Ortopediâ Rossii
Background. The leading role in long-term survival of the prosthesis installed using impaction bone grafting is given to the mechanical properties of the graft.
Vadim N. Golnik   +7 more
doaj   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

open access: yesAdvanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen   +5 more
wiley   +1 more source

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