Results 51 to 60 of about 4,808,878 (376)

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Next Steps for Hydrogen - physics, technology and the future [PDF]

open access: yes, 2016
Hydrogen has been proposed as a future energy carrier for more than 40 years. In recent decades, impetus has been given by the need to reduce global greenhouse gas emissions from vehicles.
Glowacki, Bartek   +2 more
core  

Diffusion of hydrogen within idealised grains of bcc-Fe: A kinetic Monte Carlo study

open access: yes, 2012
Structural defects in materials such as vacancies, grain boundaries, and dislocations may trap hydrogen and a local accumulation of hydrogen at these defects can lead to the degradation of the materials properties.
Drautz, Ralf   +2 more
core   +1 more source

Hydrogen enhanced thermal fatigue of y-titanium aluminide [PDF]

open access: yes, 1995
A study of hydrogen enhanced thermal fatigue cracking was carried out for a gamma-based Ti-48Al-2Cr alloy by cycling between room temperature and 750 or 900 °C.
Dunfee, William   +3 more
core   +3 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Enhanced Hydrogen Storage Properties of Li-RHC System with In-House Synthesized AlTi3 Nanoparticles

open access: yesEnergies, 2021
In recent years, the use of selected additives for improving the kinetic behavior of the system 2LiH + MgB2 (Li-RHC) has been investigated. As a result, it has been reported that some additives (e.g., 3TiCl3·AlCl3), by reacting with the Li-RHC components,
Thi-Thu Le   +6 more
doaj   +1 more source

Metallic Hydrides I: Hydrogen Storage and Other Gas-Phase Applications [PDF]

open access: yes, 2002
A brief survey is given of the various classes of metal alloys and compounds that are suitable for hydrogen-storage and energy-conversion applications.
Bowman, Robert C., Jr., Fultz, Brent
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Enabling large-scale hydrogen storage in porous media – the scientific challenges

open access: yesEnergy & Environmental Science, 2021
This article identifies and discusses the scientific challenges of hydrogen storage in porous media for safe and efficient large-scale energy storage to enable a global hydrogen economy.
N. Heinemann   +15 more
semanticscholar   +1 more source

Properties of Dense Fluid Hydrogen and Helium in Giant Gas Planets

open access: yes, 2006
Equilibrium properties of hydrogen-helium mixtures under thermodynamic conditions found in the interior of giant gas planets are studied by means of density functional theory molecular dynamics simulations.
Burrows   +14 more
core   +2 more sources

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