Results 41 to 50 of about 2,489,376 (291)
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Hydrogen bonding in 1-carboxypropanaminium nitrate
There are two crystallographically independent cations and two anions in the asymmetric unit of the title compound, C4H5NO2+·NO3−. In the crystal, the 1-carboxypropanaminium cations and nitrate anions are linked to each other through ...
Rim Benali-Cherif +3 more
doaj +1 more source
The aim of this work is to shed light on the origins of unique properties by studying the relationship between viscosity and hydrogen‐bonding interactions of terpene‐based natural deep eutectic solvents (NADES). Five systems including camphor/formic acid,
Chen Fan +3 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Guanidinium 2-(myristoylsulfanyl)ethanesulfonate
In the title compound, CH6N3+·C16H31O4S2− [systematic name: guanidinium 2-(tetradecanoylsulfanyl)ethanesulfonate], each 2-(myristoylthio)ethanesulfonate ion displays hydrogen bonding to three guanidinium counter-ions, which themselves ...
Elizabeth S. Monillas +4 more
doaj +1 more source
The conformations of 2-cyclopenten-1-ol (2CPOL) have been investigated by high-level theoretical computations and infrared spectroscopy. The six conformational minima correspond to specific values of the ring-puckering and OH internal rotation ...
Esther J. Ocola, Jaan Laane
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The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
1H-NMR and viscosity studies of hydrogen bonding of Chinese rice wine
The viscosity of Chinese rice wine gradually increases with the maturing process, resulting in a better taste due to longer contact with the tongue. Herein, the structure of water–ethanol was detected by hydrogen nuclear magnetic resonance (1H-NMR) and ...
Jingjing Cao +5 more
doaj +1 more source
Intermolecular interactions in a phenol-substituted benzimidazole
Hydrogen bonding plays an important role in the design of solid-state structures and gels with desirable properties. 1-(4-Hydroxybenzyl)-2-(4-hydroxyphenyl)-5,6-dimethyl-1H-benzimidazole was isolated as the acetone disolvate, C22H20N2O2·2C3H6O.
David K. Geiger +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

