Results 61 to 70 of about 382,475 (303)

Pyridine-2-carboximidamidate chloride monohydrate

Acta Crystallographica Section E, 2010
The title compound, C6H8N3+·Cl−·H2O, crystallizes with three formula units in the asymmetric unit. The cations are non-planar with the –C(NH2)2 groups twisted out of the ring planes.
Fei Liu, Fang Zhang, Qifan Chen, Huidong Zhang   +3 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

1,2-Diazinium hydrogen chloranilate

Acta Crystallographica Section E, 2008
In the crystal structure of the title compound, C4H5N2+·C6HCl2O4−, there are three crystallographically independent 1,2-diazinium cations and hydrogen chloranilate anions.
Kazuma Gotoh, Hiroyuki Ishida
doaj   +1 more source

Aggregation of Copper(I) and Silver(I) Chloride Phosphane Complexes Determined by Aryl‐Stacking and Weak Hydrogen Bonds in the Ligand Periphery

, 2022
Felix Müller, Andreas Mix, Hans‐Georg Stammler, Norbert W. Mitzel   +3 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

meso-5,10,15,20-Tetrakis(4-hydroxy-3-methoxyphenyl)porphyrin propionic acid monosolvate

Acta Crystallographica Section E, 2012
In the title compound, C48H38N4O8·C3H6O2, the porphyrin molecule is centrosymmetric. The propionic acid solvent molecule is disordered over two sets of sites with equal occupancy factors.
Agnieszka Leonarska, Maciej Zubko, Piotr Kuś, Joachim Kusz, Alicja Ratuszna   +4 more
doaj   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Imidazolium trans-bis(iminodiacetato-κ3O,N,O′)cobaltate(III)

Acta Crystallographica Section E, 2009
In the title compound, (C3H5N2)[Co(C4H5NO4)2], the cation and anion are located on a twofold rotation axis and inversion center, respectively. Intermolecular N—H...O hydrogen bonds link the cations and anions into layers parallel to the ab ...
Miao-Li Zhu, Li-Ping Lu, Xiao-Li Gao
doaj   +1 more source

Hydrogen Bonds of Coordinated Ethylenediamine and a Water Molecule: Joint Crystallographic and Computational Study of Second Coordination Sphere

, 2022
Jelena M. Živković, Milan R. Milovanović, Snežana D. Zarić   +2 more
openalex   +2 more sources