Results 41 to 50 of about 112,375 (261)

Single-atomic platinum on fullerene C60 surfaces for accelerated alkaline hydrogen evolution

Nature Communications, 2023
The electrocatalytic hydrogen evolution reaction (HER) is one of the most studied and promising processes for hydrogen fuel generation. Single-atom catalysts have been shown to exhibit ultra-high HER catalytic activity, but the harsh preparation ...
Ruiling Zhang, Yaozhou Li, Xuan Zhou, Ao Yu, Qi Huang, Tingting Xu, Longtao Zhu, Ping Peng, Shuyan Song, Luis Echegoyen, Fang-Fang Li   +10 more
doaj   +1 more source

Electrocatalysts for hydrogen oxidation and evolution reactions [PDF]

Science China Materials, 2016
ABSTRACT The hydrogen economy is a clean, efficient, and sustainable energy system that delivers energy using hydrogen. Electrolyzers are used to generate hydrogen, and fuel cells consume hydrogen as a fuel. These devices rely on hydrogen evolution and oxidation reactions. Catalysts are required to accelerate the reactions.
Siqi Lu, Zhongbin Zhuang
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Recent advances in alternative oxidation reactions for water splitting and their efficient electrocatalysts

工程科学学报
Developing state-of-the-art water electrolysis technologies to advance large-scale hydrogen production is an effective way to ease the current energy crisis and environmental pollution.
Miao WANG, Rongrong DENG, Qibo ZHANG
doaj   +1 more source

Co doped MoS2 as Bifunctional Electrocatalyst for Hydrogen Evolution and Oxygen Reduction Reactions

International Journal of Electrochemical Science, 2019
Pure MoS2 and MoS2 compounds were doped with Co using a hydrothermal method. XRD results indicate that two of the five diffraction peak results at 9.2° and 18.2° may be attributed to low crystallinity of MoS2. The (002) diffraction peaks for the Co-doped
Congrong Wang, Shun Wang, Jianguo Lv, Yuxuan Ma, Yongqi Wang, Gaoliang Zhou, Mingsheng Chen, Min Zhao, Xiaoshuang Chen, Lei Yang   +9 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Developments in Nanostructured MoS₂-Decorated Reduced Graphene Oxide Composite Aerogel as an Electrocatalyst for the Hydrogen Evolution Reaction

Gels
Developing lightweight, highly active surfaces with a high level of performance and great stability is crucial for ensuring the dependability of energy harvesting and conversion devices.
Sadhasivam Thangarasu, Mrunal Bhosale, Gowthami Palanisamy, Tae Hwan Oh   +3 more
doaj   +1 more source