Results 41 to 50 of about 724,754 (316)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Journal of Pharmacy and Bioallied Sciences, 2020 Introduction: Stingless bee is an insect that belongs to the family Apidae. Its name is based on its disability of stinging. It has a high product of Meliponini honey and propolis by which are commonly referred to as stingless bee honey and stingless bee
Fatima Ibrahim Jibril +2 more
doaj +1 more source
An effective palynological preparation procedure using hydrogen peroxide [PDF]
, 2007 Most pre-Quaternary palynology samples are currently prepared by demineralization of the sediment/sedimentary rock matrix using hydrochloric and hydrofluoric acids (HCl and HF respectively).
Kyffin-Hughes, Jane E. +2 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Redox Biology, 2020 Understanding how mitochondria contribute to cellular oxidative stress and drive signaling and disease is critical, but quantitative assessment is difficult. Our previous studies of cultured C2C12 cells used inhibitors of specific sites of superoxide and
Jingqi Fang +2 more
doaj +1 more source
Reduction of Fe and Ni in Fe-Ni-O systems [PDF]
Journal of Mining and Metallurgy. Section B: Metallurgy, 2013 A Cu-Co ore from Katinga Province, the Republic of Congo containing 1.5% Co and 1.6% Cu was tested to determine the leachability of Cu and Co using sulphuric acid and hydrogen peroxide mixtures at different conditions.
Zhang Y., Wei W., Yang X., Wei F.
doaj +1 more source
Concentration of Hydrogen Peroxide [PDF]
, 2006 Methods for concentrating hydrogen peroxide solutions have been described. The methods utilize a polymeric membrane separating a hydrogen peroxide solution from a sweep gas or permeate.
Parrish, Clyde F.
core +1 more source
A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells. [PDF]
, 2015 Aging is characterized by a progressive deterioration in physiological functions and metabolic processes. The loss of cells during aging in vital tissues and organs is related to several factors including oxidative stress and inflammation.
Borsani, Elisa +7 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Detection of interstellar hydrogen peroxide [PDF]
, 2011 The molecular species hydrogen peroxide, HOOH, is likely to be a key ingredient in the oxygen and water chemistry in the interstellar medium. Our aim with this investigation is to determine how abundant HOOH is in the cloud core {\rho} Oph A.
André +34 more
core +3 more sources