Results 41 to 50 of about 679,832 (288)

Persister Cell Formation and Elevated lsrA and lsrC Gene Expression upon Hydrogen Peroxide Exposure in a Periodontal Pathogen Aggregatibacter actinomycetemcomitans

open access: yesMicroorganisms, 2023
The effect of hydrogen peroxide, an antiseptic dental treatment, on Aggregatibacter actinomycetemcomitans, the main causative agent of localized invasive periodontitis, was investigated.
Yohei Nakamura   +4 more
doaj   +1 more source

A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells. [PDF]

open access: yes, 2015
Aging is characterized by a progressive deterioration in physiological functions and metabolic processes. The loss of cells during aging in vital tissues and organs is related to several factors including oxidative stress and inflammation.
Borsani, Elisa   +7 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The role of honey in the management of wounds [PDF]

open access: yes, 1999
The widespread development of antibiotic-resistant bacteria has generated an increasing interest in the use of alternate therapies for the treatment of infected wounds.
Molan, Peter C.
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Effect of non-hydrogen peroxide on antibacterial activity of Malaysian Meliponini honey against Staphylococcus aureus

open access: yesJournal of Pharmacy and Bioallied Sciences, 2020
Introduction: Stingless bee is an insect that belongs to the family Apidae. Its name is based on its disability of stinging. It has a high product of Meliponini honey and propolis by which are commonly referred to as stingless bee honey and stingless bee
Fatima Ibrahim Jibril   +2 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site IQ of complex I in diverse cell lines

open access: yesRedox Biology, 2020
Understanding how mitochondria contribute to cellular oxidative stress and drive signaling and disease is critical, but quantitative assessment is difficult. Our previous studies of cultured C2C12 cells used inhibitors of specific sites of superoxide and
Jingqi Fang   +2 more
doaj   +1 more source

Reduction of Fe and Ni in Fe-Ni-O systems [PDF]

open access: yesJournal of Mining and Metallurgy. Section B: Metallurgy, 2013
A Cu-Co ore from Katinga Province, the Republic of Congo containing 1.5% Co and 1.6% Cu was tested to determine the leachability of Cu and Co using sulphuric acid and hydrogen peroxide mixtures at different conditions.
Zhang Y., Wei W., Yang X., Wei F.
doaj   +1 more source

Oxidative Stress Detection With Escherichia Coli Harboring A katG\u27::lux Fusion [PDF]

open access: yes, 1996
A plasmid containing a transcriptional fusion of the Escherichia coli katG promoter to a truncated Vibrio fischeri lux operon (luxCDABE) was constructed. An E.
Belkin, S.   +4 more
core   +2 more sources

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