Results 81 to 90 of about 358,529 (289)

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

Advanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang, Mara Artibani, Yongcheng Jin, Aneesh Aggarwal, Yujia Zhang, Sandra Muñoz‐Galvan, Ellina Mikhailova, Lena Rai, Nobina Mukherjee, Ravinash Krishna Kumar, Ashwag Albukhari, Shaohua Ma, Linna Zhou, Ahmed Ashour Ahmed, Hagan Bayley   +14 more
wiley   +1 more source

Hydrogen peroxide generated by an atmospheric He-O2-H2O flowing post-discharge: production mechanisms and absolute quantification [PDF]

ISPC-22, Jul 2015, Antwerp, Belgium. 2015, 2016
An atmospheric plasma torch has been supplied with a gaseous mixture of helium, water vapour and/or oxygen to study the production of reactive species within its flowing post-discharge, in particular hydrogen peroxide. The mechanisms responsible for the production of H2O2 have been investigated by correlating measurements of mass spectrometry and ...
arxiv  

Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site IQ of complex I in diverse cell lines

Redox Biology, 2020
Understanding how mitochondria contribute to cellular oxidative stress and drive signaling and disease is critical, but quantitative assessment is difficult. Our previous studies of cultured C2C12 cells used inhibitors of specific sites of superoxide and
Jingqi Fang, Hoi-Shan Wong, Martin D. Brand   +2 more
doaj  

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Effects of Modification on the Structure and Functional Properties of Dietary Fiber in Burdock Root

Shipin gongye ke-ji
To improve the hydration and functional properties of dietary fiber from burdock root by ultrasonic treatment combined with hydrogen peroxide modification.
Yizhen LI, Xinxin SONG, Kaiyang MA, Jian ZHANG, Xinyi WAN, Jin FENG, Xiaoe CHEN, Ying LI, Xubo FANG   +8 more
doaj   +1 more source

Hydrogen Peroxide Induced Oxidative Damage on Mineral Density and Mechanical Properties of Bone

Brazilian Archives of Biology and Technology, 2018
Hydrogen peroxide is a common reactive oxygen species involved in the catalytic mechanism though it is toxic to cells due to its oxidative nature. This work investigates the effects of hydrogen peroxide induced oxidative damage on bone mineral density ...
Ekrem Cicek, Enes Cakmak
doaj   +1 more source

Functionalized Cerium Oxide Nanoparticles Enhance Penetration into Melanoma Spheroids In Vivo through Angiogenesis

Advanced Healthcare Materials, EarlyView.
Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu, Joel M. Yong, Robyn Yeh, Florence Bartlett, John M. Whitelock, Megan S. Lord   +5 more
wiley   +1 more source

An Intermediate Compound in the Catalase-hydrogen peroxide Reaction. [PDF]

, 1947
Britton Chance, Carl Olof Rosted, Lars Gunnar Sillén, Annikki Linnasalmi, Pentti Laukkanen   +4 more
openalex   +1 more source

Nanohybrid Hydrogel with Dual Functions: Controlled Low‐Temperature Photothermal Antibacterial Activity and Promoted Regeneration for Treating MRSA‐Infected Bone Defects

Advanced Healthcare Materials, EarlyView.
An injectable polydopamine‐based nanohybrid hydrogel integrates controlled low‐temperature photothermal therapy with potent antibacterial efficacy against MRSA while promoting robust bone regeneration. The hydrogel's composite design triggers HSP70 expression, facilitating osteogenesis and efficient bone formation.
Fang Yang, Zewen Shi, Yiwei Hu, Qian Pang, Tianyu Du, Baiyang Song, Jiaqi Zhong, Xiaodong Hu, Weilai Zhu, Junhong Chen, Lin Shi, Xianjun Chen, Qingjiang Pang, Yabin Zhu   +13 more
wiley   +1 more source

THE PRIMARY AND SECONDARY COMPOUNDS OF CATALASE AND METHYL OR ETHYL HYDROGEN PEROXIDE

, 1949
Britton Chance
  +4 more sources