Results 91 to 100 of about 97,085 (317)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

CO2 hydrogenation to methanol over zeolite-encaged mononuclear copper centers

, 2022
The selective hydrogenation of CO2 to methanol by renewable hydrogen source represents an attractive route for CO2 recycling and carbon neutral. Stable catalysts with high activity and methanol selectivity are being hotly pursued, and current debates on ...
Landong, Li, Bonan, Li, Guangjun, Wu, Naijia, Guan, Bin, Qin, Yuchao, Chai, Weili, Dai   +6 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

An Electrochemical Approach for Designing Thermochemical Bimetallic Nitrate Hydrogenation Catalysts

, 2023
Bimetallic alloy catalysts can achieve a diverse range of reactivity inaccessible to pure metals. Classically, catalytic promotion in alloy catalysts has been ascribed to atomic scale cooperativity between the metal constituents.
Ryan, Bisbey, Wei Lun, Toh, Jaeyune, Ryu, Yogesh, Surendranath, Kunal, Lodaya, Karl, Westendorff, Bryan Yuk-Wah, Tang, Yuriy, Román-Leshkov, Sophia, Weng   +8 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Hydrogenation by Iron Catalysts

, 2016
This chapter deals with hydrogenation mediated by iron metal present as supported and unsupported nanoparticles. Inspired by nature, design scientists have developed homogeneous and heterogeneous systems to perform selective hydrogenation. In the chapter,
Lojewska, Tomila,, Sa, Jacinto,
core  

Recent advances in carbon-based catalysts for CO2 hydrogenation toward circular economy

Carbon Capture Science & Technology
Thermo-catalytic CO2 hydrogenation with renewable energy-powered green H2 is one of the most promising approaches for simultaneously producing fuels and chemicals (i.e., syngas, alcohol, and olefins,) and achieve a circular carbon economy.
Hao Wen, Haiquan Liao, Xueyuan Pan, Kang Sun, Jianchun Jiang, Yanlin Liao, Xiangzhou Yuan, Hao Sun   +7 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

In Vitro Versus in Situ Ruminal Biohydrogenation of Unsaturated Fatty Acids from a Raw or Extruded Mixture of Ground Canola Seed/Canola Meal [PDF]

, 2003
Raw or extruded blends of ground canola seeds and canola meal were used to compare in vitro and in situ lag times and rates of disappearance due to ruminal biohydrogenation of unsaturated fatty acids.
Moncoulon, R., Troegeler-Meynadier, Annabelle, Eynard, P., Bayourthe, Corine, Nicot, M.C., Enjalbert, Francis, Eynard, Philippe, Nicot, Marie-Claude, Bayourthe, C., Troegeler-Meynadier, A., Enjalbert, F.   +10 more
core   +1 more source