Results 71 to 80 of about 185,465 (298)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Mechanism of Semi-Hydrogenation of Trace Acetylene in Ethylene by [MB12Hx]2-

Taiyuan Ligong Daxue xuebao
[Purposes] The main problem of semi-hydrogenation of trace acetylene in ethylene is excessive hydrogenation. High concentration of ethylene is the main cause of excessive hydrogenation, so it is important to design a catalyst with acetylene enrichment ...
CHEN Kangjie, WANG Wannan, SHI Xiufeng, REN Ruipeng, LYU Yongkang   +4 more
doaj   +1 more source

MIL‐100(Fe) Supported Pt−Co Nanoparticles as Active and Selective Heterogeneous Catalysts for Hydrogenation of 1,3‐Butadiene

ChemistryOpen, 2022
Superior catalytic performance for selective 1,3‐butadiene (1,3‐BD) hydrogenation can usually be achieved with supported bimetallic catalysts. In this work, Pt−Co nanoparticles and Pt nanoparticles supported on metal–organic framework MIL‐100(Fe ...
Prof. Lili Liu, Zhixuan Han, Yifan Lv, Prof. Chunling Xin, Prof. Xiaojing Zhou, Dr. Lei Yu, Prof. Xishi Tai   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Metal oxides and their roles in heterogeneous catalysis: special emphasis on synthesis protocols, intrinsic properties, and their influence in transfer hydrogenation reactions

SN Applied Sciences, 2023
This review emphasizes La-based metal oxides of the perovskite form and their application in heterogeneous catalytic transfer hydrogenation (CTH) reactions from year 2013. Perovskites are potential alternatives to noble metals. The possibility of induced-
Tafadzwa Precious Mabate, Nomathamsanqa Prudence Maqunga, Sinemihlali Ntshibongo, Mulisa Maumela, Ndzondelelo Bingwa   +4 more
doaj   +1 more source

Ultrasound- and microwave-assisted preparation of lead-free palladium catalysts: effects on the kinetics of diphenylacetylene semi-hydrogenation [PDF]

, 2015
The effect of environmentally benign enabling technologies such as ultrasound and microwaves on the preparation of the lead-free Pd catalyst has been studied.
Bonrath, Werner, Borretto, Emily, Cherkasov, Nikolay, Cravotto, Giancarlo, Ibhadon, Alex O., Medlock, Jonathan, Wu, Zhilin   +6 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Internal lattice oxygen sites invert product selectivity in electrocatalytic alkyne hydrogenation over copper catalysts

Nature Communications
Copper-based catalysts exhibit excellent performance of electrocatalytic alkynes hydrogenation, especially for the selective alkynes hydrogenation toward alkenes.
Mengyu Li, Yimin Jiang, Wei Chen, Yucheng Huang, Yingrui Lu, Leitao Xu, Shengkai Li, Yandong Wu, Zhongcheng Xia, Ruiqi Wang, Shuangyin Wang, Yuqin Zou   +11 more
doaj   +1 more source

Selective photocatalytic hydrogenation of citral over pure TiO 2 nanoparticle

Materials Research Express, 2022
The α , β -unsaturated aldehydes selective hydrogenation, especially the C=O bond, is an extremely challenging topic in the field of catalysis. In this paper, a series of pure TiO _2 photocatalysts obtained at various calcination temperature were tested ...
Chao Luo, Xian Liu, Tao Lai, Junyuan Li, Guoming Xia, Wennan Zou, Hongming Wang   +6 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source