Results 61 to 70 of about 119,307 (312)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dynamic modeling of three-phase upflow fixed-bed reactor including pore diffusion [PDF]

open access: yes, 2002
The dynamics of a three-phase upflow fixed-bed reactor are investigated using a non-isothermal heterogeneous model including gas–liquid and liquid–solid mass transfer and diffusion/reaction phenomena inside the catalyst.
Le Lann, Jean-Marc   +9 more
core   +1 more source

Influence of Hydrogenation on Residual Stresses of Pipeline Steel Welded Joints [PDF]

open access: yesMaterials Research, 2016
Hydrogen embrittlement is a phenomenon that affects the performance of steel used for oil and gas pipelines. This paper presents a study of the effect of hydrogenation on the residual stresses of an API 5L X65 steel pipe.
Alexandre Magno de Souza Sant'Anna   +3 more
doaj   +1 more source

2030 Ambitions for Hydrogen, Clean Hydrogen, and Green Hydrogen

open access: yesASEC 2023, 2023
Hydrogen production has been dominated by gray hydrogen (hydrogen produced from fossil fuels without carbon capture). Historical data for 2019–2021 show nearly steady global production of and demand for hydrogen, with an annual average of 92 Mt (million tonnes) for each.
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Internal lattice oxygen sites invert product selectivity in electrocatalytic alkyne hydrogenation over copper catalysts

open access: yesNature Communications
Copper-based catalysts exhibit excellent performance of electrocatalytic alkynes hydrogenation, especially for the selective alkynes hydrogenation toward alkenes.
Mengyu Li   +11 more
doaj   +1 more source

Selective Hydrogenation of 1-Hexyne Using Pd-Cu and Pd-W Supported on Alumina Catalysts

open access: yesChemical Engineering Transactions, 2013
Vinyl acetylene and 1-butyne are by products in mixed C4 separation processes and they must be eliminated due to their high flammability. However, C4 acetylene can be upgraded to higher value hydrocarbons such as 1,3-butadiene and 1-butene by using ...
P. Insorn   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Enantioselective homogeneous catalysts for the synthesis of fluorinated organic compounds [PDF]

open access: yes, 2012
This thesis is divided into three main results chapters that reflect the path my research took. In the first results chapter, the first organocatalyst for the carbonyl-ene reaction was discovered and found to give high conversion using 1,3-bis(3,5-bis ...
Jones, Charlotte E. S.
core   +1 more source

"Emulsifier-regulated synthesis of nitrile rubber and its catalytic hydrogenation in emulsion"

open access: yesHecheng xiangjiao gongye
The primary challenge in emulsion hydrogenation resides in maintaining emulsion stability under specific temperature and pressure conditions. This study proposed a strategy involving the incorporation of emulsifiers during the hydrogenation process to ...
GUO Zong-lei1 a, YU Ming-ming2, LI Yan-yan1 b, WANG Hui1 a, WANG Cheng-dong1 a
doaj   +1 more source

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