Results 151 to 160 of about 130,442 (303)

Cholesteryl ester hydrolase activity is abolished in HSL macrophages but unchanged in macrophages lacking KIAA1363[S]

open access: yesJournal of Lipid Research, 2010
Cholesteryl ester (CE) accumulation in macrophages represents a crucial event during foam cell formation, a hallmark of atherogenesis. Here we investigated the role of two previously described CE hydrolases, hormone-sensitive lipase (HSL) and KIAA1363 ...
Marlene Buchebner   +18 more
doaj  

alpha-N-Benzoylarginine-2-naphthylamide Hydrolase (Cathepsin B1 ?) from Rat Skin. II. Purification of the Enzyme and Demonstration of Two Inhibitors in the Skin. [PDF]

open access: bronze, 1975
M. Järvinen   +5 more
openalex   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes

open access: yesChemBioChem, EarlyView.
In the nascent processes of the beginnings and evolution of life, nucleobases and especially purines, ribonucleos(t)ides and primitive RNAs have been continuously modified. A RNA‐peptide world and key metabolic pathways probably have emerged from the corresponding chemical modifications resulting from adenine deamination, purine alkylation and ...
Jean‐Luc Décout   +1 more
wiley   +1 more source

Lienhwalides: Unique Tropolone–Maleidride Hybrids from Hypoxylon lienhwacheense

open access: yesChemBioChem, EarlyView.
Lienhwalides are novel tropolone–maleidride hybrid molecules unique in nature. Absolute configuration is solved by semisynthetic approaches and X‐ray analysis. Interplay between both lwt and lwm biosynthetic gene clusters is responsible for the production of lienhwalides.
Katharina Schmidt   +13 more
wiley   +1 more source

Maintaining the Integral Membrane Proteome: Revisiting the Functional Repertoire of Integral Membrane Proteases

open access: yesChemBioChem, EarlyView.
Regulated intramembrane proteolysis is crucial for functional proteome in all kingdoms of life. The task of cleaving transmembrane proteins within the unique environment of the lipid bilayer presents biochemical challenges that has been solved by integral membrane proteases (IMPRs).
Hannah Fremlén, Björn M. Burmann
wiley   +1 more source

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