Results 171 to 180 of about 157,550 (314)

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy   +4 more
wiley   +1 more source

A Robust Bioprocess for the Global Incorporation of Noncanonical Amino Acids in Auxotrophic Hosts Produces Labeled Proteins at the Gram Scale

open access: yesChemBioChem, EarlyView.
A robust bioprocess enables global incorporation of noncanonical amino acids in both shake flask and bioreactor cultures, producing gram‐per‐liter titers of efficiently labeled proteins. A versatile Escherichia coli BL21(DE3) auxotroph platform supports broad compatibility with various noncanonical amino acids and target proteins, facilitating flexible
Patrik Fladischer   +8 more
wiley   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

open access: yesChemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow   +2 more
wiley   +1 more source

Integrated and closed‐loop biorefinery strategies for efficient waste valorization and biofuel production

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Advancements in biofuel production technologies are essential for reducing global dependence on fossil fuels and addressing their overexploitation. Many valuable components of biomass, such as cellulose, hemicellulose, and lignin, remain underused in traditional biorefineries, which typically rely on a single feedstock to produce a primary ...
Marcos Paulo Patta Granado   +5 more
wiley   +1 more source

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