Histochemical Observation on Acid Hydrolase Activities in Irradiated Tumor Cells
Yukío Shimosato, Keiichi Watanabe
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Proteins of the kidney microvillar membrane. Immunoelectrophoretic analysis of the membrane hydrolases: identification and resolution of the detergent- and proteinase-solubilized forms [PDF]
Andrew Booth, Lauren Hubbard, A J Kenny
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Advancing the Exploration of the Ubiquitin‐like Protein FUBI with Synthetic Chemical Tools
This study unveils a novel synthetic platform by solid‐phase peptide synthesis for generating FUBI‐based chemical tools to investigate FUBIylation, a poorly understood ubiquitin‐like signaling process linked to cancer. By employing these innovative probes, we uncover novel FUBI interactors, paving the way for transformative insights into FUBI biology ...
Francesca D’Amico+8 more
wiley +1 more source
Role of the pneumococcal autolysin (murein hydrolase) in the release of progeny bacteriophage and in the bacteriophage-induced lysis of the host cells [PDF]
C Ronda-Laín+3 more
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Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity
N. Bright, L. Davis, J. Luzio
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Disruption of Retriever Function Impacts Retrograde Trafficking From Endosomes
ABSTRACT Within endosomes cargo proteins are sorted and packaged into endosomal‐transport carriers (ETCs) enabling their delivery to other intracellular compartments. Retromer, a conserved multimeric protein complex, has defined functions in sorting cargo mediating formation of ETCs for both retrograde trafficking back to the trans‐Golgi network (TGN ...
Zebin Li, Zhe Yang, Rohan D. Teasdale
wiley +1 more source
Peptide hydrolase activity of human intestinal mucosa in adult coeliac disease [PDF]
Adrian P. Douglas, T. J. Peters
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An enzyme that has been identified and characterized as capable of hydrolyzing paclitaxel (Taxol), a key anticancer drug derived from Pacific yew (Taxus brevifolia) has been identified. Molecular docking (MD) simulations map the catalytic triad and critical residues that drive substrate‐enzyme interactions. The findings indicate the catalytic potential
Jinfen Su+3 more
wiley +1 more source
Variation of Fructan and Its Metabolizing Enzymes in Onions with Different Storage Characteristics. [PDF]
Ueno K+4 more
europepmc +1 more source