Results 111 to 120 of about 151,216 (363)
Expanding the Toolkit for the Serine Hydrolases
Chemistry & Biology, 2015 In this issue of Chemistry & Biology, Cognetta et al. (2015) describe new pharmacological tools, including N-hydroxyhydantoin-containing carbamate inhibitors and an activity-based probe, for palmitoyl protein thioesterase 1 and alpha, beta-hydrolase domain-4 that expand the toolkit for the serine hydrolases.
Ran Wang, Matthew K. Ross
openaire +3 more sources
Comparison of lipases and glycoside hydrolases as catalysts in synthesis reactions
Applied Microbiology and Biotechnology, 2016 Lipases and glycoside hydrolases have large similarities concerning reaction mechanisms. Acyl-enzyme intermediates are formed during lipase-catalyzed reactions and in an analogous way, retaining glycoside hydrolases form glycosyl-enzyme intermediates ...
P. Adlercreutz
semanticscholar +1 more source
Advanced Science, EarlyView.This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong +5 more
wiley +1 more source
Enzymatic Diagnostics of Soil Health of the European Part of Russia with Lead Contamination
Soil SystemsLead (Pb) is one of the most common environmental pollutants. Lead has an acute toxic effect on soil biotas and the enzymatic system of soils. The objective of this study is to carry out enzymatic diagnostics of soil health in the European part of Russia
Tatiana Minnikova +5 more
doaj +1 more source
Design, Synthesis, and Application of Immobilized Enzymes on Artificial Porous Materials
Advanced Science, EarlyView.This review comprehensively summarizes the advances in research for immobilized enzymes on artificial porous materials. It highlights the advantages of bottom‐up strategy, post‐synthesis modification and composite method of metal‐organic frameworks (MOFs), covalent organic frameworks (COFs) and hydrogen‐bonded organic frameworks (HOFs) and emphasizes ...
Lu Ran +4 more
wiley +1 more source
State of enzyme systems of polymorphonuclear leukocytes by the gingival margin level correction
Кубанский научный медицинский вестник, 2015 The paper deals with the results of cytochemical studies of biologically active enzyme systems of neutrophilic granulocytes and their comparative analysis to assess the effectiveness of gingiva preparation and scalpel use for the correction of the ...
M. V. Goman +2 more
doaj
mBio, 2015 Most bacterial cells are enclosed in a single macromolecule of the cell wall polymer, peptidoglycan, which is required for shape determination and maintenance of viability, while peptidoglycan biosynthesis is an important antibiotic target.
R. Wheeler +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua +19 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2018 A synthetic approach to 1,4-imino-L-lyxitols with various modifications at the C-5 position is reported. These imino-L-lyxitol cores were used for the preparation of a series of N-(4-halobenzyl)polyhydroxypyrrolidines.
Maroš Bella +4 more
doaj +1 more source
Hydrolases in Organic Chemistry. Recent Achievements in the Synthesis of Pharmaceuticals
, 2016 : Hydrolases are versatile enzymes for synthetic purposes as they are able to catalyze multiple transformations in both aqueous medium and organic solvents.
D. Méndez-Sánchez +2 more
semanticscholar +1 more source