Results 201 to 210 of about 92,642 (284)

Quantitative Stability Evaluation of Reconstituted Azacitidine Under Clinical Storage Conditions. [PDF]

Pharmaceuticals (Basel)
Ruga S, Lombardi R, Bocci T, Armenise M, Masullo M, Lamesta C, Bava R, Castagna F, Matarese E, Di Viesti MP, Biancofiore A, Liguori G, Palma E.   +12 more
europepmc   +1 more source

Intracellular self‐assembled nanoneedles for efficient lysosomal escape and CRISPR/Cas9 mediated gene editing

BMEMat, EarlyView.
PlaMnB was formed by cytolysin A‐tumor homing peptides (THP)‐modified bacterial membranes encapsulating the clustered regularly interspaced short palindromic repeat/CRISPR‐associated protein (CRISPR/Cas9) plasmid and manganese dioxide. THP‐containing bacterial membrane enhances PlaMnB vascular permeability and tumor targeting, and after cellular ...
Chen Zhang, Nan Zhang, Ruiqi Yang, Qian Qiu, Jiaying Huang, Jingang Liu, Silu Li, Jonathan F. Lovell, He Ren, Yumiao Zhang   +9 more
wiley   +1 more source

Copper‐doped borosilicate bioactive glass coating modified bacterial cellulose functional dressing for diabetic ulcer

BMEMat, EarlyView.
For the first time, a borosilicate‐based bioactive glass coating was successfully formed on the surface of bacterial cellulose nanofibers. A copper‐doped borosilicate bioactive glass coating‐modified bacterial cellulose functional dressing was designed for the management of chronic wounds, such as diabetic ulcers.
Haiyong Ao, Dingyun Wang, Le Ma, Maohu Wang, Dongxue Zhang, Xiaowei Xun, Xidong Wu, Meili Zhang, Jiajia Zong   +8 more
wiley   +1 more source

Unhooking the Hook: Optimization of the Aurora A Targeting PROTAC <b>JB170</b> to <b>CCT400028</b>, an <i>In Vitro</i> Degrader Chemical Probe. [PDF]

J Med Chem
O'Hanlon JA, Gutsche K, Müller JE, Ranjan Prusty N, Mirza A, Roumeliotis TI, Yang H, Stubbs M, Hallett ST, Eing L, McAndrew PC, Choudhary JS, Le Bihan YV, Caldwell J, van Montfort RLM, Workman P, Wolf E, Newton GK, Evans LE.   +18 more
europepmc   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Hydrolytic instability of C-F bonds in 2,2,2-trifluoroethyl-phosphinic acid systems: formation of carboxymethylphosphinic acid derivatives. [PDF]

RSC Adv
Koucký F, Císařová I, Kotek J.
europepmc   +1 more source

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

BMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin, Wenbo Chen, Xiuqi Hou, Kai Wang, Fan Liu, Ruling Zhang, Zhong Cao, Jian Zheng   +7 more
wiley   +1 more source

Subterranean environments contribute to three‐quarters of classified ecosystem services

Biological Reviews, EarlyView.
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola, David Brankovits, Tiziana Di Lorenzo, Isabel R. Amorim, Raluca Ioana Bancila, Adrià Bellvert, Enrico Bernard, Anna Blomberg, Paulo A.V. Borges, Martina Cappelletti, Rodrigo Lopes Ferreira, Rosalina Gabriel, Diana M. P. Galassi, Laura Garzoli, Vasilis Gerovasileiou, Grant C. Hose, Kathryn L. Korbel, Simone Martino, Ana Z Miller, Nataša Mori, Veronica Nanni, Giuseppe Nicolosi, Mattia Saccò, Troy S. Sakihara, Marconi Souza Silva, Anne E. Tamalavage, Maja Zagmajster, Efraín Chávez, Christian Griebler, Pedro Cardoso, Alejandro Martínez   +30 more
wiley   +1 more source

Chemometric-assisted spectrophotometric approach for stability assessment of safinamide and its synthetic precursor in antiparkinsonian formulation with sustainability profiling. [PDF]

Sci Rep
Ibrahim EA, Saad SS, Hegazy MA, Fattah LEA, Marzouk HM.   +4 more
europepmc   +1 more source

Metal‐Free Covalent Organic Frameworks for Photocatalytic CO2 Reduction

ChemistryEurope, EarlyView.
This review presents an environmentally sustainable strategy to address the critical issue of escalating atmospheric CO2 levels. It explores the application of metal‐free covalent organic frameworks in a photocatalytic approach, offering a green and efficient strategy for carbon dioxide reduction and contributing to climate change mitigation.
Supriti Dutta, Akhtar Alam, Pekham Chakrabortty, Pradip Pachfule   +3 more
wiley   +1 more source