Results 111 to 120 of about 2,858,364 (130)
Some of the next articles are maybe not open access.
Journal of Molecular Biology, 1997
The software program, HINT (Hydropathic INTeractions), which characterizes non-polar-non-polar, polar-polar, and non-polar-polar interactions, has been used to examine subunit interface associations involved in the hemoglobin allosteric transition at a residue and atomic level. HINT differs from many other computational programs in that it is based not
Glen E. Kellogg +2 more
exaly +3 more sources
The software program, HINT (Hydropathic INTeractions), which characterizes non-polar-non-polar, polar-polar, and non-polar-polar interactions, has been used to examine subunit interface associations involved in the hemoglobin allosteric transition at a residue and atomic level. HINT differs from many other computational programs in that it is based not
Glen E. Kellogg +2 more
exaly +3 more sources
Hydropathic interaction analyses of small organic activators binding to antithrombin
Bioorganic and Medicinal Chemistry, 2004Recently we designed the first small organic ligands, sulfated flavanoids and flavonoids, that act as activators of antithrombin for accelerated inhibition of factor Xa, a key proteinase of the coagulation cascade [Gunnarsson and Desai, Bioorg. Med. Chem. Lett. (2003) 13:579].
Umesh R Desai
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Hydropathic Interactions and Protein Structure: Utilizing the HINT Force Field in Structure Prediction and Protein‐Protein Docking. [PDF]
, 2014 VCU Theses and ...
Ahmed, Mostafa H.
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Cumulative hydropathic topology of a voltage-gated sodium channel at atomic resolution [PDF]
Proteins: Structure, Function and Bioinformatics, 2020 Voltage-gated sodium channels (NavChs) are biological pores that control the ow of sodium ions through the cell membrane. In humans, mutations in genes encoding NavChs can disrupt physiological cellular activity thus leading to a wide spectrum of ...
Stephen G Waxman +2 more
exaly +2 more sources
Designing Small, Nonsugar Activators of Antithrombin Using Hydropathic Interaction Analyses
Journal of Medicinal Chemistry, 2002Conformational activation of antithrombin is a critical mechanism for the inhibition of factor Xa, a proteinase of the blood coagulation cascade, and is typically achieved with heparin, a polyanionic polysaccharide clinically used for anticoagulation.
Gunnar T, Gunnarsson, Umesh R, Desai
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ImmunoMethods, 1994
We have written a computer program to aid in the identification of interaction sites between proteins. The program compares the hydropathic profiles of the two interacting proteins and reports sites, demonstrating an exact pattern of inverted hydropathy.
C C, Maier +4 more
openaire +2 more sources
We have written a computer program to aid in the identification of interaction sites between proteins. The program compares the hydropathic profiles of the two interacting proteins and reports sites, demonstrating an exact pattern of inverted hydropathy.
C C, Maier +4 more
openaire +2 more sources
Physica A: Statistical Mechanics and its Applications, 2019
Abstract Granted that neural networks are nature’s most amazing invention, what is in second place? One candidate is the human eye, and specifically its transparent lens. Here we use the evolution of the lens’ dominant proteins to quantify subtle improvements in alpha crystallins between chickens and humans. These improvements are different in α
M.A. Moret, G.F. Zebende, J.C. Phillips
openaire +1 more source
Abstract Granted that neural networks are nature’s most amazing invention, what is in second place? One candidate is the human eye, and specifically its transparent lens. Here we use the evolution of the lens’ dominant proteins to quantify subtle improvements in alpha crystallins between chickens and humans. These improvements are different in α
M.A. Moret, G.F. Zebende, J.C. Phillips
openaire +1 more source