Results 31 to 40 of about 2,858,364 (130)

Genome‐Wide Screening and Functional Verification of the Tobacco SGR Family Identify Transcription‐Factor‐Like NtSGRL as a Negative Regulator of Tomato Yellow Leaf Curl Virus Resistance

open access: yesMolecular Plant Pathology, Volume 27, Issue 10, October 2026.
A chloroplast‐associated STAY‐GREEN protein, NtSGRL1, acts as a negative regulator of antiviral immunity in tobacco. Disruption of NtSGRL1 enhances resistance to diverse plant viruses and reveals a previously unrecognized link between chloroplast regulation and immune signalling.
Ming Gu   +10 more
wiley   +1 more source

Table1_3D Interaction Homology: Computational Titration of Aspartic Acid, Glutamic Acid and Histidine Can Create pH-Tunable Hydropathic Environment Maps.xls

open access: yes, 2021
Aspartic acid, glutamic acid and histidine are ionizable residues occupying various protein environments and perform many different functions in structures. Their roles are tied to their acid/base equilibria, solvent exposure, and backbone conformations.
Glen E. Kellogg (204170)   +1 more
core   +1 more source

Rpf‐Toxo: A Preliminary Computationally Designed Dense Granule Antigen‐Based Multi‐Epitope Vaccine Against Toxoplasma gondii

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This graphical abstract summarizes the in silico design of the multi‐epitope vaccine candidate Rpf‐Toxo (Seq4) against Toxoplasma gondii. The workflow includes antigen selection, epitope mapping, vaccine construction, structural and immunological evaluation, toll‐like receptor‐4 docking, immune simulation, safety assessment, codon optimisation and ...
Mohamad Hosein Safari   +7 more
wiley   +1 more source

Table2_3D Interaction Homology: Computational Titration of Aspartic Acid, Glutamic Acid and Histidine Can Create pH-Tunable Hydropathic Environment Maps.pdf

open access: yes, 2021
Aspartic acid, glutamic acid and histidine are ionizable residues occupying various protein environments and perform many different functions in structures. Their roles are tied to their acid/base equilibria, solvent exposure, and backbone conformations.
Glen E. Kellogg (204170)   +1 more
core   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman   +6 more
wiley   +1 more source

DataSheet1_3D Interaction Homology: Computational Titration of Aspartic Acid, Glutamic Acid and Histidine Can Create pH-Tunable Hydropathic Environment Maps.pdf

open access: yes, 2021
Aspartic acid, glutamic acid and histidine are ionizable residues occupying various protein environments and perform many different functions in structures. Their roles are tied to their acid/base equilibria, solvent exposure, and backbone conformations.
Glen E. Kellogg (204170)   +1 more
core   +1 more source

Immuno‐Informatics Design of Multi‐Epitope Vaccine Candidate Against Anaplasma phagocytophilum Using Major Surface Protein 4 (MSP‐4) Antigen

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Bovine anaplasmosis is an intracellular tick‐borne, non‐contagious disease caused by gram‐negative bacteria of the family Anaplasmataceae and order Rickettsia. Anaplasma phagocytophilum is the etiological agent for human granulocytic anaplasmosis associated with severe health implications in parts of Europe and the USA and ...
Samson Anjikwi Malgwi   +5 more
wiley   +1 more source

Table5_3D Interaction Homology: Computational Titration of Aspartic Acid, Glutamic Acid and Histidine Can Create pH-Tunable Hydropathic Environment Maps.xls

open access: yes, 2021
Aspartic acid, glutamic acid and histidine are ionizable residues occupying various protein environments and perform many different functions in structures. Their roles are tied to their acid/base equilibria, solvent exposure, and backbone conformations.
Glen E. Kellogg (204170)   +1 more
core   +1 more source

Putative Mechanisms for Initial Reaction of Anaerobic Benzene Degradation Presumably Involving a Flavoprotein

open access: yesEnvironmental Microbiology, Volume 28, Issue 8, August 2026.
Anaerobic biodegradation of benzene by sulphate‐reducing strain BzS1 was studied by combining genomics, differential proteomics and targeted metabolite analyses. Strain BzS1 has an exceptionally streamlined metabolism. A highly abundant heterotrimeric flavoprotein may add benzene to either enolpyruvate or glutaconyl‐CoA followed by channelling into the
Florin Musat   +11 more
wiley   +1 more source

Single Cell and Spatially Resolved Transcriptome and Immune Repertoire of Mouse Thymus During Aging Reveal Immunological Heterogeneity and Direction of Thymic Selection Pressure

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
A systemic single‐cell and spatially‐resolved transcriptomics and TCR sequencing analysis across the aging thymus dissects the molecular underpinnings of T cell subset dynamics. The study highlights the shifting proportions and transcriptomic profiles of T cell subsets during aging.
Jialing Fang   +14 more
wiley   +1 more source

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