Results 71 to 80 of about 289,831 (273)

Hydrophobicity and phylogeny [PDF]

Nature, 1995
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/62983/1/373565b0 ...
Naylor, Gavin J. P., Collins, Timothy M., Brown, W. W.   +2 more
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cold and Warm Denaturation of Proteins

, 2001
We introduce a simplified protein model where the water degrees of freedom appear explicitly (although in an extremely simplified fashion). Using this model we are able to recover both the warm and the cold protein denaturation within a single framework,
Caldarelli, Guido, Rios, Paolo De Los
core   +1 more source

Estimation of the solubility parameters of model plant surfaces and agrochemicals: a valuable tool for understanding plant surface interactions [PDF]

, 2012
Background Most aerial plant parts are covered with a hydrophobic lipid-rich cuticle, which is the interface between the plant organs and the surrounding environment.
AL Samuels, B Aryal, B Bhushan, BA Uhlig, BC Hancock, C Neinhuis, C Neinhuis, CE Jeffree, CH Jeffree, CM Hansen, DJ Greenhalgh, DK Kosma, DW van Krevelen, DW van Krevelen, E Domínguez, EJ Johnson, EP Parsons, F Kardel, G Kerstiens, H L, H Schott, HJ Ensikat, J Burkhardt, J Graça, JA Heredia-Guerrero, JF Villena, K Koch, L Rapley, M Dias, M Javelle, M Khayet, M Khayet, M Khayet, M Kissinger, M Nosonovsky, M Pollard, M Riederer, M Riederer, MA O’Neill, MG Wirthensohn, MG Wirthensohn, MJ Steinbauer, Mohamed Khayet, MT Tyree, MW Samaha, P Wagner, PE Kolattukudy, PE Kolattukudy, PE Kolattukudy, PJ Holloway, R Gröning, RA Burton, S Bauer, S Pandey, T Eichert, T Scherbatskoy, TH Jones, TH Yeats, V Fernández, V Fernández, Victoria Fernández, VY Senichev   +61 more
core   +8 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Piacentinu Ennese PDO cheese as reservoir of promising probiotic bacteria [PDF]

, 2019
Piacentinu Ennese is a protected designation of origin (PDO) cheese produced in the surrounding area of Enna (Sicily, Italy), using raw ewe’s milk without the addition of any starter cultures.
Caggia, Cinzia, De Angelis, Maria, Pino, Alessandra, Randazzo, Cinzia Lucia, Russo, Nunziatina, Sferrazzo, Giuseppe, Van Hoorde, Koenraad   +6 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Study of the Lipid Profile of ATCC and Clinical Strains of Staphylococcus aureus in Relation to Their Antibiotic Resistance

Molecules, 2019
A number of reports have indicated a relationship between bacterial resistance to antibiotics and their lipid composition. In the present study, we characterized the lipid profiles of American Type Culture Collection (ATCC) and clinical strains of ...
Carlo Bisignano, Giovanna Ginestra, Antonella Smeriglio, Erminia La Camera, Giuseppe Crisafi, Flavio A. Franchina, Peter Q. Tranchida, Angela Alibrandi, Domenico Trombetta, Luigi Mondello, Giuseppina Mandalari   +10 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Effect of Leaf Surface Waxes on Leaf Colonization by Pantoea agglomerans and Clavibacter michiganensis

Molecular Plant-Microbe Interactions, 2002
To evaluate the influence of leaf cuticular waxes on bacterial colonization of leaves, bacterial colonization patterns were examined on four glossy maize (Zea mays L.) mutants that were altered in their cuticular wax biosynthesis.
Lise M. Marcell, Gwyn A. Beattie
doaj   +1 more source