Novel Multitarget Hydroxamic Acids with a Natural Origin CAP Group against Alzheimer’s Disease: Synthesis, Docking and Biological Evaluation [PDF]
Pharmaceutics, 2021 Hydroxamic acids are one of the most promising and actively studied classes of chemical compounds in medicinal chemistry. In this study, we describe the directed synthesis and effects of HDAC6 inhibitors.
Margarita Neganova +10 more
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Synthesis and structure-activity relationships of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives as 5-lipoxygenase inhibitors [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Oxazolidinone hydroxamic acid derivatives were synthesised and evaluated for inhibitory activity against leukotriene (LT) biosynthesis in three in vitro cell-based test systems and on direct inhibition of recombinant human 5-lipoxygenase (5-LO). Thirteen
Oludotun A. Phillips +2 more
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Antibiotics and other naturally occurring hydroxamic acids and hydroxamates [PDF]
Pure and Applied Chemistry, 1971 Abstract
Hubert Maehr
openaire +3 more sources
Methods for Hydroxamic Acid Synthesis. [PDF]
Curr Org Chem, 2019 Substituted hydroxamic acid is one of the most extensively studied pharmacophores because of their ability to chelate biologically important metal ions to modulate various enzymes, such as HDACs, urease, metallopeptidase, and carbonic anhydrase. Syntheses and biological studies of various classes of hydroxamic acid derivatives have been reported in ...
Alam MA.
europepmc +4 more sources
Effect of Suberoylanilide Hydroxamic Acid and Phytosulfokine-Alpha on Successful Plant Regeneration from Embryogenic Callus-Derived Protoplasts of Garlic (<i>Allium sativum</i> L.). [PDF]
Int J Mol SciStelmach-Wityk K +4 more
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Preparation of poly hydroxamic acid from poly (styrene –methyl metha acrylate) and study of the kinetics of nickel ion sorption by the prepared acid [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2021 In this paper, the copolymer (styrene-methyl methacrylate) was prepared by using free radical polymerization for the copolymerization between methyl methacrylate and styrene in an equal molar mixing ratio and using benzoyl peroxide as a starter at a ...
Fatima Ibrahim, Saddaa Abedullah
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Exploration of Structure-Activity Relationship Using Integrated Structure and Ligand Based Approach: Hydroxamic Acid-Based HDAC Inhibitors and Cytotoxic Agents. [PDF]
Turk J Pharm Sci, 2023 Shirbhate E +4 more
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Chiral Hydroxamic Acid Ligands in the Asymmetric Synthesis of Natural Products
Chemistry, 2023 Chiral hydroxamic acid (HA) and bis-hydroxamic acid (BHA) ligands have made significant contributions to the field of asymmetric synthesis, particularly in the synthesis of natural products.
Tushar Janardan Pawar +3 more
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SYNTHESIS AND IDENTIFICATION FOR SOME FERRIC COMPLEXES OF HYDROXAMIC ACID. [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2013 The aim of this research is to prepare and identification of the hydroxamic acid derivatives of diethyl succinate which are considered as selective ligands of the Iron (III) . The synthesis of hydroxamic acid derivatives was performed as described in the
ISMAEEL KH. AL-KATEEB +2 more
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Powdery mildew (Blumeria graminis f. sp. tritici) infection and amount of key defence chemicals - cyclic hydroxamic acids - of field cultivated wheat (Triticum aestivum L.) [PDF]
Journal of Central European Agriculture, 2020 Cultivated wheat varieties have different degrees of resistance against powdery mildew. Cyclic hydroxamic acids are key defence chemicals of wheat. Examinations comprised the measurement of cyclic hydroxamic acid content and powdery mildew infection of ...
Péter Makleit +2 more
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