Results 31 to 40 of about 30,744 (233)
Biochemical characterization and selective inhibition of β-carotene cis-trans isomerase D27 and carotenoid cleavage dioxygenase CCD8 on the strigolactone biosynthetic pathway [PDF]
, 2015 The first three enzymatic steps of the strigolactone biosynthetic pathway catalysed by β-carotene cis-trans isomerase Dwarf27 (D27) from Oryza sativa and carotenoid cleavage dioxygenases CCD7 and CCD8 from Arabidopsis thaliana have been reconstituted in ...
Abe +43 more
core +2 more sources
Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity [PDF]
, 2016 Background: Histone deacetylase inhibitors (HDACi) exert multiple cytotoxic actions on cancer cells. Currently, different synthetic HDACi are in clinical use or clinical trials; nevertheless, since both pro-invasive and anti-invasive activities have been
Andrade, Ricardo +6 more
core +4 more sources
DETERMINAÇÃO DO TEOR DE BIODIESEL EM DIESEL EMPREGANDO O ENSAIO COLORIMÉTRICO DO ÁCIDO HIDROXÂMICO
Química Nova, 2015 The aim of this paper was to use colorimetric assays for hydroxamic acid to quantify the biodiesel content in diesel and compare it with the traditional method (infrared spectroscopy, using the EN 14078 method).
Roberta P. M. da Costa +4 more
doaj +1 more source
Results in Chemistry, 2021 This present study reports some natural products and one hydroxamic acid synthetic compound which were previously reported as matrix metalloproteinase-9 (MMP-9) inhibitors to be evaluated for their inhibition toward severe acute respiratory syndrome ...
Maywan Hariono +6 more
doaj +1 more source
Inhibition of histone deacetylase as a treatment for cardiac hypertrophy [PDF]
, 2005 The present invention provides for methods of treating and preventing cardiac hypertrophy. Class II HDACs, which are known to participate in regulation of chromatin structure and gene expression, have been shown to have beneficial effects on cardiac ...
Bristow, Michael R. +3 more
core +1 more source
Synthesis and HDAC inhibitory activity of pyrimidine-based hydroxamic acids
Beilstein Journal of Organic Chemistry, 2022 Histone deacetylases (HDACs) play an essential role in the transcriptional regulation of cells through the deacetylation of nuclear histone and non-histone proteins and are promising therapeutic targets for the treatment of various diseases.
Virginija Jakubkiene +6 more
doaj +1 more source
Inhibitors of bacterial and plants urease [PDF]
, 2013 Urease is an important virulence factor for Helicobacter pylori and Proteus mirabilis as well as in environmental transformations of certain nitrogenous compounds.
Macegoniuk, Katarzyna
core +1 more source
Pharmaceutics, 2021 Hydroxamic acids are one of the most promising and actively studied classes of chemical compounds in medicinal chemistry. In this study, we describe the directed synthesis and effects of HDAC6 inhibitors.
Margarita Neganova +10 more
doaj +1 more source
Silicon, endophytes and secondary metabolites as grass defenses against mammalian herbivores [PDF]
, 2014 Article Accepted Date: 30 August 2014 Acknowledgments This study was supported by the Academy of Finland (grant no. 133495 to Otso Huitu; grants no. 137909 and 110658 to Kari Saikkonen) and by the NERC (grant no. NE/F003994/1 to Xavier Lambin).
Forbes, Kristian M +8 more
core +2 more sources
Haematologica, 2010 Background Chronic lymphocytic leukemia is a neoplastic disorder that arises largely as a result of defective apoptosis leading to chemoresistance.
Basile Stamatopoulos +5 more
doaj +1 more source