Results 51 to 60 of about 30,744 (233)

Photoinduced Electron Transfer in Ruthenium Bipyridyl Complexes: Evidence for the Existence of a Cage with Molecular Oxygen [PDF]

, 2004
Ruthenium complexes with three bipyridyl ligands, one of which is modified by attaching one or two hydroxamic acids groups (Ru-1 and Ru-2, respectively), were synthesized.
Arad-Yellin, Rina, Shanzer, Abraham, Weiner, Lev, Yavin, Eylon   +3 more
core   +1 more source

Design and Synthesis of Polyamine‐Proteolysis Targeting Chimera Conjugates for Histone Deacetylase (HDAC) Degradation with Enhanced Cellular Uptake

ChemistryOpen, EarlyView.
In this article, proteolysis targeting chimeras (PROTACs) bearing a polyamine linker capable of crossing cancer cell membranes via the polyamine transport system are synthesized and evaluated. The results provide valuable insights for the design of PROTACs with enhanced cellular uptake efficiency.
Yanran Liu, Wentian Chen, Yanwei Shang, Chaonan Tang, Xianming Zeng, Jun Li, Wenting Du   +6 more
wiley   +1 more source

A Comprehensive Review of Adsorbents for Rare Earth Separation: Design, Synthesis, Adsorption Performance, and Mechanisms

Rare Metals, EarlyView.
ABSTRACT Rare earth elements (REEs) play an irreplaceable role in modern technology and industry. However, due to the highly similar physicochemical properties among REEs, their separation remains a significant challenge. Additionally, REEs often exist in low‐concentration solutions, making efficient REE recovery an urgent task.
Miao‐Miao Huang, Jun Tan, Liu‐Yin Xia, Kai Han, Hong‐Yan Cai, Xin Ma, Shuai Wang   +6 more
wiley   +1 more source

Synthesis of Pyrrolo[1,2-a]pyrimidine Enantiomers via Domino Ring-Closure followed by Retro Diels-Alder Protocol

Molecules, 2017
From 2-aminonorbornene hydroxamic acids, a simple and efficient method for the preparation of pyrrolo[1,2-a]pyrimidine enantiomers is reported. The synthesis is based on domino ring-closure followed by microwave-induced retro Diels-Alder (RDA) protocols,
Beáta Fekete, Márta Palkó, Matti Haukka, Ferenc Fülöp   +3 more
doaj   +1 more source

Interaction of solid organic acids with carbon nanotube field effect transistors [PDF]

, 2006
A series of solid organic acids were used to p-dope carbon nanotubes. The extent of doping is shown to be dependent on the pKa value of the acids. Highly fluorinated carboxylic acids and sulfonic acids are very effective in shifting the threshold voltage
Ali Afzali, Anantram, Avouris, Bradley, Chen, Christian Klinke, Collins, Covington, Derycke, Dukovic, Eberson, Freedman, Fuhrer, Heinze, Kazaoui, Kim, Klinke, Klinke, Mann, Martel, Martel, McBee, O’Connell, Phaedon Avouris, Radosavljevic, Shimauchi, Strano, Tans, Ventura   +28 more
core   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Laboratory tumor lysis syndrome complicating LBH589 therapy in a patient with acute myeloid leukaemia

Haematologica, 2008
LBH589 is a novel cinnamic hydroxamic acid analog (HAA) pan-histone deacetylase inhibitor (HDACi) currently in early phase clinical development.
A. Kalff, J. Shortt, J. Farr, R. McLennan, A. Lui, J. Scott, A. Spencer   +6 more
doaj   +1 more source

Synthesis Optimization of L-Aspartic acid β-hydroxamate by a novel Enzyme, β-Aspartyl-γ-glutamyl transferase [PDF]

, 2015
L-Aspartic acid β-hydroxamate or L-β-Aspartyl hydroxamate (BAH), water soluble- chemical compound currently obtains popularity due to its role in several important biochemical processes and to its bioactivities.
Naohara, Ryosuke, Nonomura, Yuki, Prihanto, Asep Awaludin, Takagi, Kazuyoshi, Wakayama, Mamoru   +4 more
core  

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Urea Enhanced Aquathermolysis of Heavy Oil Catalyzed by Hydroxamic Acid-Co(II) Complex at Low Temperature

MATEC Web of Conferences, 2016
To develop effective water-soluble catalyst for aquathermolysis, a phenyl hydroxamic acid-Co( II ) complex was synthesized using hydroxamic acid and CoCl2. The effects of water content and catalyst concentration on aquathermolysis were investigated.
Wu Ya, Li Yongfei, Chen Gang, Zhao Wei, Zhang Jie   +4 more
doaj   +1 more source