Results 61 to 70 of about 30,527 (215)
Antiradical, Chelating and Antioxidant Activities of Hydroxamic Acids and Hydroxyureas
Reactive oxygen species, along with reactive nitrogen species, may play an important role in the pathogenesis and progress of many diseases, including cancer, diabetes and sickle cell disease.
Branka Zorc +3 more
doaj +1 more source
Rare earth element is an important strategic metal, but the supply of high purity rare earth ores is growing slowly, which is in sharp contradiction with the rapidly growing demand. Froth flotation has been confirmed to be an effective method to separate
Longhua Xu +7 more
doaj +1 more source
Examining the PM6 semiempirical method for pKa prediction across a wide range of oxyacids [PDF]
The pK~a~ estimation ability of the semiempirical PM6 method was evaluated across a broad range of oxyacids and compared to results obtained using the SPARC software program.
Kaya Forest +2 more
core +1 more source
Safety and preliminary efficacy of vorinostat with R-EPOCH in high-risk HIV-associated non-Hodgkin\u27s lymphoma (AMC-075) [PDF]
We performed a phase I trial of vorinostat (VOR) given on days 1 to 5 with R-EPOCH (rituximab plus etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin hydrochloride) in patients with aggressive HIV-associated non-Hodgkin lymphoma.
Aboulafia, David +12 more
core +2 more sources
Carbamates as Potential Prodrugs and a New Warhead for HDAC Inhibition
We designed and synthesized carbamates of the clinically-approved HDAC (histone deacetylase) inhibitor vorinostat (suberoylanilide hydroxamic acid, SAHA) in order to validate our previously-proposed hypothesis that these carbamates might serve as ...
Kristina King +4 more
doaj +1 more source
Trichostatin A (TSA) and suberoylanilide hydroxamic acid (SAHA) were reported in our recent publication as novel human high density lipoprotein (HDL) receptor CD36 and Lysosomal integral membrane protein-II Analogous-1 (CLA-1) up-regulators. As part of a
Yu Du +6 more
doaj +1 more source
Speciation and Mobilization of Toxic Heavy Metal Ions by Methanogenic Bacteria [PDF]
HWRIC Project HWR 92 ...
Conver, Shawn +5 more
core
Citation: 'hydroxamic acids' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02911 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Hydroxamic acids are emerging as versatile chiral ligands for metal-catalyzed asymmetric oxidations due to their tunable electronic and steric environments.
Marco Valtierra-Galván +6 more
doaj +1 more source
The Broad Spectrum HDAC Inhibitor PCI-24781 Induces Caspase- and ROS-Dependent Apoptosis and is Synergistic with Bortezomib in Lymphoma [PDF]
We investigated the cytotoxicity and biology of the novel broad-spectrum hydroxamic acid-based histone deacetylase inhibitor (HDACi), PCI-24781. PCI-24781 was studied alone and combined with bortezomib in Hodgkin lymphoma (L428) and non-Hodgkin's ...
Andrew Evens +9 more
core +1 more source

