Results 91 to 100 of about 21,152 (225)

Lactylation in colorectal cancer: Unveiling novel mechanisms in metabolism, progression and therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Lactate accumulation links metabolic reprogramming to epigenetic regulation via protein lactylation. Lactylation drives colorectal cancer proliferation, metastasis, immune escape and chemoresistance. Microbiota‐derived lactate shapes a tumour‐specific lactylation landscape in colorectal cancer.
Ming Liu, Weiwei Li, Yi Ji, Yanqing Chen, Guoli Wei, Jiege Huo, Tao Gui   +6 more
wiley   +1 more source

Microbial metabolites in tumor epigenetic regulation

iMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

The use of nano/micro-layers, self-healing and slow release coatings to prevent corrosion and biofouling [PDF]

, 2014
The mitigation of corrosion and biofouling is a challenge. Through application of chemicals and special techniques can slow these undesired processes, an effective resolution requires a multidisciplinary approach involving scientists, engineers, and ...
Ai, Alagta, Aldcroft, Andrews, Aramaki, Aramaki, Avis, Baier, Baum, Bergsson, Berkeley, Beyenal, Blodgett, Blodgett, Borenstein, Borisova, Boura, Cassie, Choi, Collazo, Crundwell, Córdoba-Torres, Dafforn, Dai, Deflorian, Deng, Desimone, Dias, Edge, Fedrizzi, Feng, Gaines, García, Garrett, Ghareba, Ghosh, Ghosh, Gold, Grigoriev, Grundmeier, Guarda, Hao, Hart, He, Hong, Hoque, Hoque, Hutt, Ishibashi, Javaherdashti, Javaherdashti, Jennings, Jones, Kaesche, Kear, Kearns, Keller, Kelly, Keszthelyi, Kumar, Kuznetsov, Laibinis, Lambert, Langmuir, Lee, Lewandowski, Li, Little, Liu, Lorenz, Lusk, Ma, Mahapatro, Malayoglu, Mansfeld, Marcus, Marcus, Marcus, Mauldin, McCafferty, McIlroy, Mekhalif, Metikoš-Huković, Miale, Mihm, Mok, Montemor, Motornov, Murphy, Nesterova, Nesterova, Neumann, Nordstierna, Nuzzo, Pilbáth, Podszun, Raman, Raman, Reybuck, Rigó, Rocca, Románszki, Románszki, Románszki, Románszki, Románszki, Románszki, Rong, Ruan, Sahoo, Samadzadeh, Samadzadeh, Sanchez, Sanchez-Amaya, Scully, Selvakumar, Shchukin, Sherar, Shin, Sinapi, Skrivanova, Sonawane, Song, Stack, Su, Sun, Sun, Szabó, Sørensen, Tan, Tan, Tao, Telegdi, Telegdi, Telegdi, Telegdi, Telegdi, Telegdi, Telegdi, Telegdi, Thomas, Tong, Tremont, Tremont, Tsutsumi, Valentinelli, Videla, Wallström, Walton, Wang, Wang, Wang, Wang, Wenzel, Whelan, White, Wilhelmy, Wu, Yamamoto, Yang, Yang, Young, Yuan, Yuan, Zhang, Zhang, Zhang, Zhang, Zhao, Zheludkevich, Zheludkevich, Zheludkevich, Zisman   +172 more
core   +1 more source

A Comprehensive Review of Adsorbents for Rare Earth Separation: Design, Synthesis, Adsorption Performance, and Mechanisms

Rare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Rare earth elements (REEs) play an irreplaceable role in modern technology and industry. However, due to the highly similar physicochemical properties among REEs, their separation remains a significant challenge. Additionally, REEs often exist in low‐concentration solutions, making efficient REE recovery an urgent task.
Miao‐Miao Huang, Jun Tan, Liu‐Yin Xia, Kai Han, Hong‐Yan Cai, Xin Ma, Shuai Wang   +6 more
wiley   +1 more source

Synthesis Optimization of L-Aspartic acid β-hydroxamate by a novel Enzyme, β-Aspartyl-γ-glutamyl transferase [PDF]

, 2015
L-Aspartic acid β-hydroxamate or L-β-Aspartyl hydroxamate (BAH), water soluble- chemical compound currently obtains popularity due to its role in several important biochemical processes and to its bioactivities.
Naohara, Ryosuke, Nonomura, Yuki, Prihanto, Asep Awaludin, Takagi, Kazuyoshi, Wakayama, Mamoru   +4 more
core  

Production of hydroxamic acids by immobilized Pseudomonas aeruginosa cells Kinetic analysis in reverse micelles [PDF]

, 2013
Intact cells from Pseudomonas aeruginosa strain L10 containing amidase were used as biocatalysts both free and immobilized in a reverse micellar system.
Bernardo, Marisa, Karmali, Amin, Pacheco, Rita, Serralheiro, Maria Luísa M.   +3 more
core   +1 more source

Pharmacological Effects of Anthranilic Hydroxamic Acid and Certain Other Hydroxamic Acids

Experimental Biology and Medicine, 1960
SummaryThe hydroxamate of anthranilic acid injected intraperitoneally into rats in a dose of 1.0 mg/g causes anesthesia lasting 10 hours or more. Recovery is apparently complete. One half this dose causes tranquilization and suppression of the conditioned avoidance response. The compound protects mice against twice the lethal dose of strychnine.
F. Bernheim, J. K. Stoops
openaire   +1 more source

Chromatin remodeling agents for cancer therapy [PDF]

, 2008
Alterations in chromatin structure profoundly influence gene expression during normal cellular homeostasis and malignant transformation. Methylation of cytosines within CpG islands located in promoter and proximal coding regions facilitates recruitment ...
Cinti, Caterina, Estenoz, Mariela, Giordano, Roberto, La Sala, Dario, Magnano, Anna   +4 more
core   +1 more source

Nucleic acid binding affinity and antioxidant activity of N-m-Tolyl-4-Chlorophenoxyacetohydroxamicacid

Scientific Reports
Hydroxamic acids represent a group of weak organic acids, both naturally occurring and synthetically derived, characterized by the general formula RC(= O)N(R’OH).
Rubi Khilari, Sohilkhan Chauhan, Mamta Tripathi, Rama Pande, Mohammed S. Alqahtani, Rabbani Syed, Mudassar Shahid, Devashish Das, Avijit Sarkar   +8 more
doaj   +1 more source

Crystal structure of N-hydroxypicolinamide monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2016
The crystal structure of the title compound, C6H6N2O2·H2O, consists of N-hydroxypicolinamide and water molecules connected through O—H...O and N—H...N hydrogen bonds.
Inna S. Safyanova, Kateryna A. Ohui, Irina V. Omelchenko   +2 more
doaj   +1 more source