Results 71 to 80 of about 21,152 (225)
Development of a Bestatin-SAHA Hybrid with Dual Inhibitory Activity against APN and HDAC
With five histone deacetylase (HDAC) inhibitors approved for cancer treatment, proteolysis-targeting chimeras (PROTACs) for degradation of HDAC are emerging as an alternative strategy for HDAC-targeted therapeutic intervention.
Jiangying Cao +7 more
doaj +1 more source
Photoinduced Electron Transfer in Ruthenium Bipyridyl Complexes: Evidence for the Existence of a Cage with Molecular Oxygen [PDF]
Ruthenium complexes with three bipyridyl ligands, one of which is modified by attaching one or two hydroxamic acids groups (Ru-1 and Ru-2, respectively), were synthesized.
Arad-Yellin, Rina +3 more
core +1 more source
Hybrid networks combining natural and synthetic polymers into one network may result in networks with good bioactivity, suitable mechanical properties, and high control over degradation. This study shows that phase‐separated networks are obtained with the collagen phase acting as multifunctional crosslinks.
Agustin Rios de Anda +10 more
wiley +1 more source
The maize rhm1 mutant resists Bipolaris maydis, the causal agent of Southern corn leaf blight, by producing small necrotic lesions surrounded by chlorotic haloes.
Carl R. Simmons +6 more
doaj +1 more source
Novel class of Bi(iii) hydroxamato complexes: synthesis, urease inhibitory activity and activity against H. pylori. [PDF]
Reaction of Bi(NO3)3 with benzohydroxamic acid (Bha) and salicylhydroxamic acid (Sha) gives the novel Bi(iii) complexes [Bi2(Bha-1H)2(μ-Bha-1H)2(η(2)-NO3)2] () and [Bi6(CH3OH)2(η(1)-NO3)2(η(2)-NO3)(OH2)2(Sha-1H)12](NO3)2 ().
Fitzgerald-Hughes, Deirdre +3 more
core +1 more source
Citation: 'hydroxamic acids' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.H02911 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Methods for Hydroxamic Acid Synthesis [PDF]
Substituted hydroxamic acid is one of the most extensively studied pharmacophores because of their ability to chelate biologically important metal ions to modulate various enzymes, such as HDACs, urease, metallopeptidase, and carbonic anhydrase. Syntheses and biological studies of various classes of hydroxamic acid derivatives have been reported in ...
openaire +2 more sources
Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama +2 more
wiley +1 more source
Preparation and Characterization of Pectin Hydroxamates from Citrus Unshiu Peels
Pectin was extracted from unshiu orange (Citrus unshiu) peels and was subjected to chemical modification using hydroxamic acid. The structural and physical properties of the resulting derivatives were investigated as a function of hydroxamic acid content
In Young Bae +3 more
doaj
Synthesis and herbicidal evaluation of N-cinnamoyl-N-substituted hydroxylamine and its derivatives
The group of cinnamon and hydroxylamine produces significant results in the field of agriculture. So, the combination of both groups in the compound performs effective results in numerous fields of the medicinal and chemical industry.
Ajay Kumar +4 more
doaj +1 more source

