Results 91 to 100 of about 7,346 (216)
Assessment of cellular cobalamin metabolism in Gaucher disease
BMC Medical Genetics, 2020 Background Gaucher disease (GD) is a lysosomal disorder caused by biallelic pathogenic mutations in the GBA1 gene that encodes beta-glucosidase (GCase), and more rarely, by a deficiency in the GCase activator, saposin C.
Suelen Porto Basgalupp +6 more
doaj +1 more source
Nasal Drug Delivery Systems: An Overview [PDF]
, 2015 Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R. +3 more
core +1 more source
Journal of Inherited Metabolic Disease, Volume 48, Issue 1, January 2025.Abstract Cobalamin C (Cbl‐C) defect causes methylmalonic acidemia, homocystinuria, intellectual disability and visual impairment, despite treatment adherence. While international guidelines recommend parenteral hydroxocobalamin (OH‐Cbl) as effective treatment, dose adjustments remain unclear.
Giorgia Olivieri +10 more
wiley +1 more source
Elevated methemoglobin levels in patients treated with high-dose hydroxocobalamin [PDF]
, 2023 Martinus Dyrud +2 more
openalex +1 more source
Efficacy of methylcobalamin to normalise elevated homocysteine of vitamin B12 deficient vegetarians: a double blind placebo control study [PDF]
, 2015 Vegetarians are known to be deficient in vitamin B12, due to a lack of dietary animal products, which can elevate plasma total homocysteine (tHcy). Elevated total tHcy can render vegetarians susceptible to cardiovascular disease (CVD).
Chappell, David +3 more
core +1 more source
Analysis of Methylcobalamin and Hydroxocobalamin by HPLC/MS. Method Validation
, 2023 Stanislav V. Yefimov
openalex +1 more source
Journal of Veterinary Internal Medicine, 2020 Background In humans, absorption and tissue retention rates of intramuscularly administered hydroxocobalamin (OH‐Cbl) are superior compared to cyanocobalamin (CN‐Cbl). Supplementation with OH‐Cbl has not been described in cats.
Peter H. Kook +2 more
doaj +1 more source
Spectrophotometric analysis of purple urine secondary to methylene blue and hydroxocobalamin co-administration [PDF]
, 2023 Jeremy Hardin +4 more
openalex +1 more source
Cysteine and cysteine-related signaling pathways in arabidopsis thaliana [PDF]
, 2014 Cysteine occupies a central position in plant metabolism because it is a reduced sulfur donor molecule involved in the synthesis of essential biomolecules and defense compounds.
Aroca Aguilar, Ángeles +5 more
core +1 more source
Effect of vitamin B12 derivatives on urinary excretion of methylmalonic acid in liver diseases [PDF]
, 1970 1. Twenty.one patients with liver diseases were studied for their urinary mehylmalonic acid excretion after a valine load by means of an improved thin layer chromatography. 2.
Taketa, Kazuhisa, Ueda, Masatoshi
core +1 more source