Isolation of Cyanide Hydratase Mutants from Gloeocerospora Sorghi at alkaline pH [PDF]
Cyanide is both a useful and dangerous chemical compound that serves as a crucial component in multiple industrial processes, including metal mining.
Lessen, Henry Joseph
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Role of inorganic nitrate and nitrite in driving nitric oxide-cGMP-mediated inhibition of platelet aggregation in vitro and in vivo [PDF]
This is the peer reviewed version of the article, which has been published in final form at [doi: 10.1111/jth.12711. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.Nitric oxide (NO ...
Apostoli, GL+4 more
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Microangiopathic thrombocytopenia caused by vitamin B12 deficiency responding to plasma exchange
Summary A young adult African American female presented with normocytic microangiopathic haemolytic anaemia, elevated lactate dehydrogenase and thrombocytopenia. The patient responded to therapeutic plasma exchanges (TPE) for presumed thrombotic microangiopathy caused by thrombotic thrombocytopenic purpura (TTP).
Denis M. Dwyre+5 more
wiley +1 more source
Contributions of Sequence and Structure to Ligand Selectivity in Class II Cobalamin Riboswitches [PDF]
Riboswitches are gene regulatory elements found in the 5’-untranslated region of many bacterial genes. The direct binding of small molecule ligands induces conformational changes in the RNA that influence downstream expression machinery and determine the
Webster, Samantha M
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Comparative analysis of gene and disease selection in genomic newborn screening studies
Abstract Genomic newborn screening (gNBS) is on the horizon given the decreasing costs of sequencing and the advanced understanding of the impact of genetic variants on health and diseases. Key to ongoing gNBS pilot studies is the selection of target diseases and associated genes to be included.
Isabel R. Betzler+8 more
wiley +1 more source
Hydroxocobalamin: Physiological Retention in the Dog
SummaryHydroxocobalamin, when injected intramuscularly into dogs, produces more prolonged elevation of serum Vit. B12 than does injection of equal quantities of cyanocobalamin.
Hanus Edward J+3 more
openaire +2 more sources
Efficacy of methylcobalamin to normalise elevated homocysteine of vitamin B12 deficient vegetarians: a double blind placebo control study [PDF]
Vegetarians are known to be deficient in vitamin B12, due to a lack of dietary animal products, which can elevate plasma total homocysteine (tHcy). Elevated total tHcy can render vegetarians susceptible to cardiovascular disease (CVD).
Chappell, David+3 more
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Background In humans, absorption and tissue retention rates of intramuscularly administered hydroxocobalamin (OH‐Cbl) are superior compared to cyanocobalamin (CN‐Cbl). Supplementation with OH‐Cbl has not been described in cats.
Peter H. Kook+2 more
doaj +1 more source
Nasal Drug Delivery Systems: An Overview [PDF]
Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R.+3 more
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Hydroxocobalamin. II. Absorption from the Site of Injection and Uptake by the Liver and Calf Muscle in Man [PDF]
George B. Jerzy Glass+2 more
openalex +1 more source