Results 81 to 90 of about 7,346 (216)
Microbial Biotechnology, Volume 18, Issue 6, June 2025.Molecular and functional experiments highlight the relevance of species‐specific polymorphisms in a B12 riboswitch of the Mycobacterium genus. This information provided proof‐of‐concept to engineer a whole‐cell biosensor capable of detecting vitamin B12. ABSTRACT Vitamin B12 metabolism differs among members of the Mycobacterium genus.
Elena Campos‐Pardos +6 more
wiley +1 more source
Role of inorganic nitrate and nitrite in driving nitric oxide-cGMP-mediated inhibition of platelet aggregation in vitro and in vivo [PDF]
, 2014 This is the peer reviewed version of the article, which has been published in final form at [doi: 10.1111/jth.12711. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.Nitric oxide (NO ...
Apostoli, GL +4 more
core +1 more source
Journal of Diabetes Investigation, Volume 16, Issue 6, Page 1020-1027, June 2025.The concomitant use of metformin and PPI was significantly associated with an increased risk of vitamin B12 deficiency in patients with type 2 diabetes. ABSTRACT Introduction Vitamin B12 deficiency is one of the adverse drug reactions of metformin and proton pump inhibitors (PPIs).
Choungwon Jung, Soyoung Park, Hyunah Kim
wiley +1 more source
Military Medical Research, 2019 Inhalation injury is often associated with burns and significantly increases morbidity and mortality. The main toxic components of fire smoke are carbon monoxide, hydrogen cyanide, and irritants.
Tian-Tian Yan +5 more
doaj +1 more source
Axial Ligation and Redox Changes at the Cobalt Ion in Cobalamin Bound to Corrinoid Iron-Sulfur Protein (CoFeSP) or in Solution Characterized by XAS and DFT [PDF]
, 2016 A cobalamin (Cbl) cofactor in corrinoid iron-sulfur protein (CoFeSP) is the primary methyl group donor and acceptor in biological carbon oxide conversion along the reductive acetyl-CoA pathway.
Dau, Holger +6 more
core +3 more sources
Emergency Management of Intoxication‐Type Inherited Metabolic Disorders
Journal of Inherited Metabolic Disease, Volume 48, Issue 2, March 2025.ABSTRACT In many intoxication‐type inherited metabolic disorders, the accumulation of the toxic chemical can cause acute life‐threatening emergencies. Sometimes this is the inevitable consequence of a severe metabolic defect, but it is often triggered by catabolism.
J. Dexter Tarr, Andrew A. M. Morris
wiley +1 more source
Isolation of Cyanide Hydratase Mutants from Gloeocerospora Sorghi at alkaline pH [PDF]
, 2013 Cyanide is both a useful and dangerous chemical compound that serves as a crucial component in multiple industrial processes, including metal mining.
Lessen, Henry Joseph
core +1 more source
Potassium channel‐mediated NO‐induced vasodilation during maturation: Dominance of Kv7 channels
FASEB BioAdvances, Volume 7, Issue 3, March 2025.Scheme illustrating the key findings: Potassium channels, even multiple ones, contribute to SNP‐induced vasorelaxation in young and adult rats and these channels change from Kv1 and Kv7 channels to BKCa and Kv7 channels during postnatal development.
Anastasia A. Shvetsova +4 more
wiley +1 more source
Contributions of Sequence and Structure to Ligand Selectivity in Class II Cobalamin Riboswitches [PDF]
, 2016 Riboswitches are gene regulatory elements found in the 5’-untranslated region of many bacterial genes. The direct binding of small molecule ligands induces conformational changes in the RNA that influence downstream expression machinery and determine the
Webster, Samantha M
core +2 more sources
SignatureFinder enables sequence mining to identify cobalamin‐dependent photoreceptor proteins
The FEBS Journal, Volume 292, Issue 3, Page 635-652, February 2025.The authors show the utility of their computational tool, available at https://enzymeevolver.com, for the identification of novel photoreceptors. Signature residues for the binding of the green‐light‐sensitive cofactor adenosylcobalamin were determined.
Yuqi Yu +10 more
wiley +1 more source