Results 141 to 150 of about 72,897 (256)

Engineering Flexible Nanofibrous Hydroxyapatite Scaffolds With Tunable Degradation and Mechanical Properties for Bone Regeneration

open access: yesSmall, EarlyView.
Conventional hydroxyapatite ceramics are brittle and poorly resorbable, limiting their use in bone repair. To overcome these limitations, flexible scaffolds are fabricated using ceramic nanofibers as structural building blocks. Adjusting nanofiber characteristics allows modulating the mechanical properties and degradation, providing a versatile ...
Raúl Agut López   +4 more
wiley   +1 more source

A Luminescent PEI/Cy5‐Citrate‐Functionalized Carbonated Apatite Nanoplatform for In Vitro Gene Delivery and In Vivo Traceability

open access: yesSmall, EarlyView.
A luminescent PEI/Cy5‐citrate‐functionalized carbonated apatite nanoplatform combines biocompatibility, plasmid delivery, and Cy5‐based traceability. The system enables effective in vitro gene delivery while preserving cell viability and allows real‐time in vivo fluorescence tracking of the nanocarrier.
Laura Garrido Martín   +5 more
wiley   +1 more source

Engineering an Enzymatically Active Granular Matrix for On‐Chip Modeling of Bone‐Like Mineralization

open access: yesSmall, EarlyView.
Alkaline phosphatase (ALP)‐functionalized poly(ethylene glycol) (PEG) microgels assemble into a perfusable granular matrix for cell‐free modeling of bone‐like mineralization. Microgel‐associated enzymatic activity promotes calcium phosphate deposition, producing a calcium‐deficient, poorly crystalline apatite‐like phase, while keeping interparticle ...
Farhad Sanaei   +6 more
wiley   +1 more source

Synthesis, modification, and chlorhexidine loading of polymer modified‐HM‐HAP particles: In vivo antibacterial analysis and cell cytotoxicity assessment

open access: yesSmart Molecules, EarlyView.
This study presents the synthesis of hollow mesoporous hydroxyapatite (HM‐HAP) particles modified with different weights PEG and PEI. Chlorhexidine was loaded onto the particles. SEM analysis confirmed no significant morphological changes. Antibacterial activity was tested in vitro and in vivo using mouse oral bacteria, demonstrating promising results.
Farishta Shafiq   +6 more
wiley   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário   +8 more
wiley   +1 more source

Mechanochemical Synthesis of a TiO<sub>2</sub>-Containing Biogenic Hydroxyapatite Ceramic Composite: Balancing Antibiofilm Efficacy and Fibroblast Cytocompatibility. [PDF]

open access: yesJ Funct Biomater
Fernández-Conde D   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy