Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako +16 more
wiley +1 more source
Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner +8 more
wiley +1 more source
Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li +7 more
wiley +1 more source
Bone tumor-homing nanotherapeutics for prolonged retention in tumor microenvironment and facilitated apoptotic process via mevalonate pathway inhibition. [PDF]
Kang NW +8 more
europepmc +1 more source
Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang +12 more
wiley +1 more source
Removal of Cd2+ from aqueous solutions by hydroxyapatite
Ronghai Zhu +5 more
openalex +2 more sources
AI Guided Protein Design for Next‐Generation Autogenic Engineered Living Materials
Autogenic engineered living materials (ELMs) integrate biology and materials science to create self‐regenerating and self‐healing materials. This perspective highlights emerging strategies in protein engineering and AI‐guided de novo design to expand the capabilities of autogenic ELMs.
Hoda M. Hammad, Anna M. Duraj‐Thatte
wiley +1 more source
Calcifying nanoparticles induce apoptosis and calcification in bone marrow mesenchymal stem cells <i>via</i> the transforming growth factor-β/Smad pathway. [PDF]
Su XL +11 more
europepmc +1 more source
The influence of single and binary mixtures of collagen amino acids on the structure of synthetic calcium hydroxyapatite as a nanobiomaterial. [PDF]
Krukowski S, Sztelmach K.
europepmc +1 more source
Effect of Processing on Morphology of Hydroxyapatites: Bioactive Glasses and Crystalline Composites [PDF]
Recent studies on multinary oxides for applications as laser hosts and high dielectric capacitors have shown that processing at high temperature provides glassy or crystalline materials based on thermal treatments and cooling rates. Since hydroxyapatites
Arnold, Bradley +9 more
core +1 more source

