Results 41 to 50 of about 1,896 (188)

Antiproliferative activity of synthesized dibutyltin(IV) hydroxybenzoate derivatives against A549, MCF-7, and HeLa human cancer cells

Journal of Nigerian Society of Physical Sciences
The adverse effects associated with conventional cancer therapies have intensified the search for anticancer agents with fewer side effects. One approach involves the synthesis of organotin(IV) hydroxybenzoates.
Sutopo Hadi, Ermin K. Winarno, Susanto Susanto, Khairun N. Berawi, Susianti Susianti, Noviany Noviany, Wasinton Simanjuntak, Dede Komarudin, Hendig Winarno   +8 more
doaj   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

Synthesis of 3-Alkyl- and 3-Chloroalkyl-2-hydroxybenzoates Based on [3+3] Cyclizations of 4-Alkyl- and 4-Chloroalkyl-1,3-bis(trimethylsilyloxy)buta-1,3-dienes

, 2006
The TiCl4-mediated [3+3] cyclization of 4-alkyl- and 4-chloroalkyl-1,3-bis(trimethylsilyloxy)buta-1,3-dienes with 3-silyl­alk-2-en-1-ones afforded 3-alkyl- and 3-chloroalkyl-2-hydroxybenzoates, respectively; the latter containing a remote chloride ...
Bellur, Esen, Appel, Bettina, Nguyen Thi Hong, Van, Langer, Peter   +3 more
core   +1 more source

Hydroxybenzoic acid isomers and the cardiovascular system [PDF]

Nutrition Journal, 2014
Today we are beginning to understand how phytochemicals can influence metabolism, cellular signaling and gene expression. The hydroxybenzoic acids are related to salicylic acid and salicin, the first compounds isolated that have a pharmacological activity.
Juurlink, Bernhard HJ, Azouz, Haya J, Aldalati, Alaa MZ, AlTinawi, Basmah MH, Ganguly, Paul   +4 more
openaire   +2 more sources

Volatile Organic Compounds Emitted by Fungi Have Substantial Effects on Growth and Disease Resistance in Arabidopsis thaliana

Plant, Cell &Environment, Volume 49, Issue 9, Page 7168-7190, September 2026.
ABSTRACT Volatile organic compounds (VOCs) emitted by certain fungi have previously been suggested to modulate plant development and their response to stresses. While some fungal species, such as Trichoderma harzianum, are known to produce VOCs, the production of VOCs in other phylogenetically divergent species, such as Mucor mucedo, was previously ...
Sara Yugueros, Asier Largo‐Gosens, Cristina Úbeda, Cristina Hernández‐Fernández, Alba Manga‐Robles, Diego Rebaque, Antonio Encina, Hugo Mélida   +7 more
wiley   +1 more source

Reimagining Lignin Valorization: Synthetic Biology–Enabled Sustainable Aromatic Carbon Biomanufacturing

Advanced Science, Volume 13, Issue 47, 24 August 2026.
The diagram illustrates a sustainable model of lignin valorization and carbon cycling based on microbial cell factories. Using lignin as the feedstock, synthetic biology technologies, including depolymerization, cell factory construction, pathway gene module integration, and metabolic network regulation, are applied to convert lignin into bulk ...
Na Li, Jun‐Jie Zhangyang, Bing‐Zhi Li, Zhi‐Hua Liu, Ying‐Jin Yuan   +4 more
wiley   +1 more source

Regulation of the 5-HT3A receptor-mediated current by alkyl 4-hydroxybenzoates isolated from the seeds of Nelumbo nucifera

, 2018
Four known alkyl 4-hydroxybenzoates, i.e., methyl 4-hydroxybenzoate (1), ethyl 4-hydroxybenzoate (2), propyl 4-hydroxybenzoate (3), and butyl 4-hydroxybenzoate (4), were isolated from the seeds of Nelumbo nucifera GAERTNER (Nymphaeaceae) for the first ...
서은경
core   +1 more source

Overcoming resistance in lung cancer: combined mitochondrial destabilization by lipophilic cations and doxycycline in hypoxic non-small cell lung carcinoma

Frontiers in Pharmacology
IntroductionLung cancer remains the leading cause of cancer-related mortality worldwide. Drug resistance is a major limitation of current therapies, prompting the search for new treatment strategies.
Mabel Catalán, Mabel Catalán, Denny Vidal, Alfredo Molina-Berríos, Javiera Carrasco-Rojas, Rodrigo López-Muñoz, Gisella Vásquez, Ivonne Olmedo, Ivonne Olmedo, José A. Jara   +9 more
doaj   +1 more source

p-Hydroxybenzoic Acid Synthesis in Mycobacterium tuberculosis [PDF]

Journal of Biological Chemistry, 2005
Glycosylated p-hydroxybenzoic acid methyl esters and structurally related phenolphthiocerol glycolipids are important virulence factors of Mycobacterium tuberculosis. Although both types of molecules are thought to be derived from p-hydroxybenzoic acid, the origin of this putative biosynthetic precursor in mycobacteria remained to be established.
Stadthagen, G., Korduláková, J., Griffin, R., Constant, P., Bottová, I., Barilone, Nathalie, Gicquel, B., Daffé, M., Jackson, M.   +8 more
openaire   +3 more sources

COQ2‐Associated Primary Coenzyme Q10 Deficiency Presenting With Proteinuria: A Case Report and Literature Review

Molecular Genetics &Genomic Medicine, Volume 14, Issue 7, July 2026.
We report a female pediatric patient with compound heterozygous *COQ2* variants (c.368G>A, c.908A>G) presenting PCOQ10D; high‐dose CoQ10 plus enalapril maleate resolved proteinuria and preserved renal function. ABSTRACT Background Primary coenzyme Q10 (CoQ10) deficiency (PCOQ10D) is an autosomal recessive mitochondrial disorder caused by pathogenic ...
Yuqi Yue, Fei Zhao, Qiuxia Chen
wiley   +1 more source