Results 41 to 50 of about 1,633 (150)

Identification of Key Genes Involved in Lactic Acid Metabolism in Periodontitis Based on Bioinformatics Analysis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Lactic acid metabolism correlates with periodontitis progression. Using machine learning (LASSO and SVM‐RFE) on GSE16134 and GSE173078 datasets, CFI and COQ2 were identified as key genes, with good diagnostic performance (AUC > 0.75). GSEA linked these genes to MAPK signalling, endocytosis, and ubiquitin‐mediated proteolysis.
Bijun Zhu, Shi Xu, Mingyue Cheng, Leiying Miao   +3 more
wiley   +1 more source

UPO‐Mimetic Engineering of CYP199A4 Enables Enhanced Peroxygenase Activity via the Hydrogen Peroxide Shunt Pathway

ChemistryEurope, Volume 4, Issue 3, March 2026.
P450 goes peroxide: When one base just isn’t basic enough. Engineering a second basic residue into CYP199A4T252E boosts its peroxygenase activity but also makes it sensitive to H2O2. The double mutant F182R/T252E shows increased turnover before rapidly self‐destructing, revealing the fine balance between productive peroxide activation and oxidative ...
Pablo Velázquez García, Thomas Hilberath, Peter‐Leon Hagedoorn, Frank Hollmann   +3 more
wiley   +1 more source

Engineering 2‐Pyrone‐4,6‐Dicarboxylic Acid Production Reveals Metabolic Plasticity of Poplar

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1398-1413, March 2026.
ABSTRACT Woody biomass is a promising source of fermentable sugars for biofuels and bio‐based chemicals, but its industrial use is limited by the costly biorefinery process. A viable strategy to reduce costs involves enhancing both biomass processability and the generation of high‐value co‐products.
Nidhi Dwivedi, Pingping Ji, Yang Tian, Dasmeet Kaur, Vijaya Kumar Reddy Vulavala, Yuki Tobimatsu, Aymerick Eudes, Chang‐Jun Liu   +7 more
wiley   +1 more source

Reducing the Sinapine Levels of Camelina sativa Seeds Through Targeted Genome Editing of REF1

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1839-1865, March 2026.
ABSTRACT Sinapine (O‐sinapoyl choline) is the major phenolic metabolite typically found in the oil‐rich seeds of Brassicaceae such as Camelina sativa and Brassica napus. It imparts a bitter taste to the seeds as a defence mechanism against herbivores, but it also renders them less palatable to livestock.
Amélie A. Kelly, Martin Fulda, Merle Aden, Ilka N. Abreu, Kirstin Feussner, Ivo Feussner   +5 more
wiley   +1 more source

Sustainable Porous Carbon Derived from Lignin for High‐Performance CO2 Capture

Chemistry – An Asian Journal, Volume 21, Issue 4, 25 February 2026.
Lignin‐derived porous carbons offer a sustainable and scalable route for high‐performance CO2 capture. By tailoring ultramicroporosity, hierarchical pore networks, and heteroatom functionalities through chemical activation, templating, and hybrid methods, adsorption capacity and selectivity can be optimized. This review correlates.
Kiet Le Anh Cao, Oktaviardi Bityasmawan Abdillah, Tomoyuki Hirano, Eka Lutfi Septiani, Takashi Ogi   +4 more
wiley   +1 more source

Cu‐Catalyzed Aerobic Oxidative C─C Cleavage in Lignin‐Derived Oligomers and Biological Funneling of the Monomeric Products

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Catalytic aerobic oxidation under aqueous alkaline conditions promotes C–C cleavage in pine‐ and poplar‐derived lignin oligomers, accessing high yields of aromatic monomers. The monomeric phenols obtained from this process then undergo effective biological conversion into cis,cis‐muconic acid and 2‐pyrone‐4,6‐dicarboxylic acid using engineered strains ...
Surajudeen Omolabake, Dillon T. Hofsommer, Kathryn M. Mains, Chad T. Palumbo, Davide Rigo, Allison Z. Werner, Gregg T. Beckham, Shannon S. Stahl   +7 more
wiley   +1 more source

Exploring the Syntheses for Phenolic Acid Esters of Cellulose: Pros and Cons of Methods. [PDF]

Polym Sci Technol
Elschner T, Schönrich J, Fischer S.
europepmc   +1 more source

Biosourced Functional Hydroxybenzoate-<i>co</i>-Lactide Polymers with Antimicrobial Activity. [PDF]

J Am Chem Soc
Salas-Ambrosio P, Vexler S, P Sivasankaran R, Vlahakis N, Lai RS, Johnson C, Baas-Maynard SI, Min DS, Lower H, Doyle AG, Tang Y, Rodriguez JA, Chen IA, Read de Alaniz J, Maynard HD.   +14 more
europepmc   +1 more source

Engineering <i>Pseudomonas taiwanensis</i> for efficient chorismate-based production of mono- and dihydroxybenzoates. [PDF]

Metab Eng Commun
Kofler F, Schwanemann T, Teófilo da Silva N, Wierckx N, Wynands B.   +4 more
europepmc   +1 more source

Quantitative decoding of coupled carbon and energy metabolism in Pseudomonas putida for lignin carbon utilization. [PDF]

Commun Biol
Zhou N, Wilkes RA, Chen X, Teitel KP, Belgrave JA, Beckham GT, Werner AZ, Yu Y, Aristilde L.   +8 more
europepmc   +1 more source