Results 11 to 20 of about 57,632 (243)

Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: a multi-center observational study

BMC Infectious Diseases, 2021
Background Hydroxychloroquine has not been associated with improved survival among hospitalized COVID-19 patients in the majority of observational studies and similarly was not identified as an effective prophylaxis following exposure in a prospective ...
Andrew Ip, Jaeil Ahn, Yizhao Zhou, Andre H. Goy, Eric Hansen, Andrew L. Pecora, Brittany A. Sinclaire, Urszula Bednarz, Michael Marafelias, Ihor S. Sawczuk, Joseph P. Underwood, David M. Walker, Rajiv Prasad, Robert L. Sweeney, Marie G. Ponce, Samuel La Capra, Frank J. Cunningham, Arthur G. Calise, Bradley L. Pulver, Dominic Ruocco, Greggory E. Mojares, Michael P. Eagan, Kristy L. Ziontz, Paul Mastrokyriakos, Stuart L. Goldberg   +24 more
doaj   +1 more source

The effect of favipiravir versus hydroxychloroquine on clinical and laboratory findings in COVID-19 in healthcare workers

Brazilian Journal of Infectious Diseases, 2022
Objectives: Comparative data on hydroxychloroquine and favipiravir, commonly used agents in the treatment of Coronavirus Disease-2019 (COVID-19), are still limited.
Derya Bayırlı Turan, Mehtap Menteş, Yıldıran Özel, Kıvanç Şerefhanoğlu, Burcu Aydoğan, Neşe İbil, Füsun Güneşdoğdu, Hijran Mammadova Orucova, Cüneyt Saltürk, Hakan Çelik   +9 more
doaj   +1 more source

Hydroxychloroquine: a comprehensive review and its controversial role in coronavirus disease 2019

Annals of Medicine, 2021
Hydroxychloroquine, initially used as an antimalarial, is used as an immunomodulatory and anti-inflammatory agent for the management of autoimmune and rheumatic diseases such as systemic lupus erythematosus.
Pankaj Bansal, Amandeep Goyal, Austin Cusick, Shubham Lahan, Harpal S. Dhaliwal, Poonam Bhyan, Pradnya Brijmohan Bhattad, Fawad Aslam, Sagar Ranka, Tarun Dalia, Lovely Chhabra, Devang Sanghavi, Bhavin Sonani, John M. Davis   +13 more
doaj   +1 more source

A call to caution when hydroxychloroquine is given to elderly patients with COVID-19

International Journal of Infectious Diseases, 2021
Introduction: Use of hydroxychloroquine in patients with coronavirus disease 2019 (COVID-19) was widespread and uncontrolled until recently. Patients vulnerable to severe COVID-19 are at risk of hydroxychloroquine interactions with co-morbidities and co ...
Julian J. Gabor, Andrea Kreidenweiss, Stefan Weber, Moaaz Salama, Mihaly Sulyok, Zita Sulyok, Erik Koehne, Meral Esen, Benno Kreuels, Parichehr Shamsrizi, Erwin Biecker, Benjamin Mordmüller, Christoph P. Berg, Stefano Fusco, Carsten Köhler, Stefan Kubicka, Jens Leitlein, Marylyn Addo, Michael Ramharter, Matthias Schwab, Alfred Lennart Bissinger, Thirumalaisamy P. Velavan, Sanjeev Krishna, Peter G. Kremsner   +23 more
doaj   +1 more source

Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy

Arthritis & Rheumatology, 2020
ObjectiveIn 2016, the American Academy of Ophthalmology (AAO) changed the recommended daily dose of hydroxychloroquine (HCQ) from 6.5 mg/kg to <5 mg/kg. However, it is not clear that the lower prescribed dose of HCQ will have the same efficacy for systemic lupus erythematosus (SLE) activity or the same role in protecting against cardiovascular risk ...
Michelle Petri, Marwa Elkhalifa, Jessica Li, Laurence S. Magder, Daniel W. Goldman   +4 more
openaire   +3 more sources

Is Hydroxychloroquine with Azithromycin a Good Combination in COVID-19 Compared to Hydroxychloroquine Alone from Cardiac Perspective? A Systematic Review and Meta-Analysis

Journal of Nepal Health Research Council, 2021
Background: The global spread of COVID-19 and the lack of definite treatment have caused an alarming crisis in the world. We aimed to evaluate the outcome and potential harmful cardiac effects of hydroxychloroquine and azithromycin compared to ...
Pravash Budhathoki, Dhan Bahadur Shrestha, Sitaram Khadka, Era Rawal   +3 more
doaj   +1 more source

Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.

PLoS ONE, 2022
Preeclampsia is a multi-system disease that can have severe, even fatal implications for the mother and fetus. Abnormal placentation can lead to ischaemic tissue injury and placental inflammation.
Elif Kadife, Natalie Hannan, Alesia Harper, Natalie Binder, Sally Beard, Fiona C Brownfoot   +5 more
doaj   +2 more sources

The effect of hydroxychloroquine on glucose control and insulin resistance in the prediabetes condition

Advanced Biomedical Research, 2016
Background: Hydroxychloroquine can improve most underlying coronary risk factors; however, there are a few studies on the effects of hydroxychloroquine on blood glucose and insulin resistance.
Fahimeh Sheikhbahaie, Masoud Amini, Mojgan Gharipour, Ashraf Aminoroaya, Nader Taheri   +4 more
doaj   +1 more source

Association of hydroxychloroquine and cardiac arrhythmia in patients with systemic lupus erythematosus: A population-based case control study.

PLoS ONE, 2021
ObjectivesHydroxychloroquine is widely used to treat certain viral and rheumatic diseases including systemic lupus erythematosus. Cardiac arrhythmia is an important safety issue with hydroxychloroquine.
Chien-Hsien Lo, Yu-Hsun Wang, Chin-Feng Tsai, Kuei-Chuan Chan, Li-Ching Li, Tse-Hsien Lo, James Cheng-Chung Wei, Chun-Hung Su   +7 more
doaj   +1 more source

Diagnostic pitfalls and laboratory test interference after hydroxychloroquine intoxication: A case report

Toxicology Reports, 2019
Hydroxychloroquine is a medication used to treat autoimmune conditions. Overdoses of hydroxychloroquine are uncommon, with most recommendations on monitoring drawing from experience with more common overdoses of the related drug chloroquine. We present a
Joshua B. Radke, Jennie M. Kingery, Jon Maakestad, Matthew D. Krasowski   +3 more
doaj   +1 more source