Results 21 to 30 of about 57,833 (235)

How different is the status of depression and anxiety in patients with rheumatoid arthritis receiving methotrexate with sulfasalazine or hydroxychloroquine?

Russian Open Medical Journal, 2023
Background — Depression and anxiety are among the most common clinical manifestations in patients with rheumatoid arthritis (RA). Sulfasalazine and hydroxychloroquine are important medications used to treat these patients.
Mansour Babaei, Mehdi Dorparvar, Behnaz Yousef Ghahari, Behzad Heidari, Hemmat Gholinia, Sussan Moudi   +5 more
doaj   +1 more source

Data on hydroxychloroquine interference with urine laboratory testing

Data in Brief, 2019
Hydroxychloroquine is a medication used to treat rheumatoid arthritis, systemic lupus erythematosus, and other autoimmune disorders. Previous studies have shown that hydroxychloroquine and the structurally related drug chloroquine have the potential to ...
Jennie M. Kingery, Joshua B. Radke, Jon Maakestad, Matthew D. Krasowski   +3 more
doaj   +1 more source

Effect of hydroxychloroquine on glycemic variability in type 2 diabetes patients uncontrolled on glimepiride and metformin therapy

Indian Journal of Endocrinology and Metabolism, 2022
Background and Aims: No study to date has assessed the effect of hydroxychloroquine on various parameters of glycaemic variability. To assess the effect of hydroxychloroquine on glycaemic variability in type 2 diabetes patients uncontrolled on ...
Rajesh Rajput, Suyasha Saini, Siddhant Rajput, Parankush Upadhyay   +3 more
doaj   +1 more source

Hydroxychloroquine inhibits the growth of lung cancer cells by inducing G1 cell cycle arrest and apoptosis

Pakistan Journal of Pharmaceutical Sciences
Hydroxychloroquine, used initially as an anti-malarial drug, is now recognized for its anti-tumor effects in a range of human cancers. Nevertheless, there has been limited attention given to the molecular mechanisms of anti-tumor action of ...
Shuang Fu, Likun Liu, Yaoyao Wang, Wenlu Liu, Siyu Sun, Xiu li Gao, Wenbin Zhu, Liling Yue   +7 more
doaj   +1 more source

Hydroxychloroquine Improves Obesity-Associated Insulin Resistance and Hepatic Steatosis by Regulating Lipid Metabolism

Frontiers in Pharmacology, 2019
The burden of obesity and associated cardiometabolic diseases has been considered as an important risk factor for lupus patients. Therefore, whether obesity is involved in the over-activation of autoimmune response has attracted more and more attention ...
Xin Qiao, Zhuo-Chao Zhou, Rui Niu, Yu-Tong Su, Yue Sun, Hong-Lei Liu, Jia-Lin Teng, Jun-Na Ye, Hui Shi, Cheng-De Yang, Xiao-Bing Cheng   +10 more
doaj   +1 more source

ChemoPROphyLaxIs with hydroxychloroquine For covId-19 infeCtious disease (PROLIFIC) to prevent covid-19 infection in frontline healthcare workers: A structured summary of a study protocol for a randomised controlled trial

Trials, 2020
Objectives Primary objective To determine whether chemoprophylaxis with hydroxychloroquine versus placebo increases time to contracting coronavirus disease 2019 (COVID-19) in frontline healthcare workers.
Carmel M. McEniery, Marie Fisk, Karen Miles, Fotini Kaloyirou, Evangelia Vamvaka, Annette Hubsch, Jane Smith, Ian B. Wilkinson, Joseph Cheriyan   +8 more
doaj   +1 more source

The effect of hydroxychloroquine on cholesterol metabolism in statin treated patients after myocardial infarction

Atherosclerosis Plus, 2023
Background and aims: To evaluate the effect of hydroxychloroquine (HCQ) on serum and lipoprotein lipids and serum biomarkers of cholesterol synthesis and absorption in myocardial infarction patients with a high-dose statin. Methods: Myocardial infarction
Lotta Ulander, Piia Simonen, Heli Tolppanen, Otto Hartman, Tuomas T. Rissanen, Kari K. Eklund, Marita Kalaoja, Mika Kurkela, Mikko Neuvonen, Mikko Niemi, Janne T. Backman, Helena Gylling, Juha Sinisalo   +12 more
doaj   +1 more source

The C-C Chemokine Receptor Type 4 Is an Immunomodulatory Target of Hydroxychloroquine

Frontiers in Pharmacology, 2020
The emergence of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19) in China, reported to the World Health Organization on December 31, 2019, has led to a large global pandemic and is a major public health issue.
Tyler C. Beck, Tyler C. Beck, Tyler C. Beck, Kyle R. Beck, Calvin B. Holloway, Richard A. Hemings, Thomas A. Dix, Russell A. Norris   +7 more
doaj   +1 more source

Hydroxychloroquine reduces metastatic tumor burden in pancreatic adenocarcinoma through myeloperoxidase inhibition

Journal of Inflammation
Background Metastatic pancreatic adenocarcinoma has a 5-year survival of only 3%. Neutrophil extracellular traps are formed when neutrophils expel their intracellular contents and have been intricately linked to metastases.
Britney Niemann, Pavan Rao, Quinn Hopen, Kaitlyn Landreth, Angisha Basnet, Werner Geldenhuys, Tracy W. Liu, Brian A. Boone   +7 more
doaj   +1 more source

Interaction of Hydroxychloroquine with Pharmacokinetically Important Drug Transporters

Pharmaceutics, 2020
(1) Background: Hydroxychloroquine is used to treat malaria and autoimmune diseases, and its potential use against COVID-19 is currently under investigation.
Johanna Weiss, Gzona Bajraktari-Sylejmani, Walter E. Haefeli   +2 more
doaj   +1 more source