Results 71 to 80 of about 2,824 (172)

Hydroxycitrate delays early mortality in mice and promotes muscle regeneration while inducing a rich hepatic energetic status

Aging Cell, Volume 23, Issue 9, September 2024.
ATP citrate lyase (ACLY) inhibitors have been proposed as calorie restriction mimetics. We performed a longevity assay in mice using the ACLY inhibitor hydroxycitrate. We observed that hydroxycitrate delays early mortality, having pleiotropic effects in muscle and liver physiology.
Isabel Espadas, María Ángeles Cáliz‐Molina, Raúl López‐Fernández‐Sobrino, Concepción Panadero‐Morón, Alejandro Sola‐García, Mario Soriano‐Navarro, Enrique Martínez‐Force, Mónica Venegas‐Calerón, Joaquin J. Salas, Franz Martín, Benoit R. Gauthier, Clara Alfaro‐Cervelló, David Martí‐Aguado, Vivian Capilla‐González, Alejandro Martín‐Montalvo   +14 more
wiley   +1 more source

Aqueous and ethanolic extracts of welsh onion, Allium fistulosum, attenuate high-fat diet-induced obesity

BMC Complementary and Alternative Medicine, 2018
Background Allium fistulosum (Welsh onion) is a traditional medicinal plant used for the treatment of colds, influenza, abdominal pain, headache, and heart disease. This study evaluated the effects of A.
Yoon-Young Sung, Dong-Seon Kim, Seung-Hyung Kim, Ho Kyoung Kim   +3 more
doaj   +1 more source

Updates on Antiobesity Effect of Garcinia Origin (−)-HCA [PDF]

, 2020
Garcinia is a plant under the family of Clusiaceae that is commonly used as a flavouring agent. Various phytochemicals including flavonoids and organic acid have been identified in this plant.
Oon Li, Chuah, Wan Yong Ho, Swee Keong Yeap, Boon Kee Beh   +4 more
core  

Inhibition of hypoxia‐inducible factors suppresses subretinal fibrosis

The FASEB Journal, Volume 38, Issue 13, 15 July 2024.
Genetic modulation of hypoxia‐inducible factors (major: HIF‐1α; minor: HIF‐2α) in retinal pigment epithelial (RPE) cells reduces the development of pathologic choroidal neovascularization (CNV) and subretinal fibrosis in age‐related macular degeneration through the improvement of the epithelial–mesenchymal transition (EMT) process of RPE cells ...
Chiho Shoda, Deokho Lee, Yukihiro Miwa, Satoru Yamagami, Hiroyuki Nakashizuka, Kazumi Nimura, Kazutoshi Okamoto, Hirokazu Kawagishi, Kazuno Negishi, Toshihide Kurihara   +9 more
wiley   +1 more source

Three new substituted cinnamoyl hydroxycitric acids from corn plant.

Agricultural and Biological Chemistry, 1977
Three new substituted cinnamoyl hydroxycitric acids have been isolated from corn plant (Zea mays L.) and their structures established as 2-O-trans-p-coumaroyl-(2S, 3S)-hydroxycitric acid (I), 2-O-trans-feruloyl-(2S, 3S)-hydroxycitric acid (II), and 2-O-trans-caffeoyl- (2S, 3S)-hydroxycitric acid (III) on the basis of spectroscopic and chemical evidence.
OZAWA, Tetsuo, NISHIKIORI, Takaaki, TAKINO, Yoshinori   +2 more
openaire   +2 more sources

The First Comprehensive Chemical Profiling of Vachellia gummifera (Willd.) Kyal. & Boatwr., a Plant with Medicinal Value

Chemistry &Biodiversity, Volume 21, Issue 6, June 2024.
Abstract Vachellia gummifera (Willd.) Kyal. & Boatwr. is a medicinal plant endemic to Morocco that has no documented studies on its chemical composition. In this study, the chemical composition of the water/methanol (4 : 1) extracts of air‐dried leaf and stem samples of Moroccan V. gummifera was determined using UHPLC‐MS and NMR.
Musa Kisiriko, Clarice Noleto‐Dias, Gabin T. M. Bitchagno, Imane Naboulsi, Maria Anastasiadi, Leon A. Terry, Mansour Sobeh, Michael H. Beale, Jane L. Ward   +8 more
wiley   +1 more source

Screening of Hydroxycitric Acid-Producing Microorganisms and Genome Shuffling for the Improved Production

, 2005
P(論文)ヒドロキシクエン酸(HCA)は熱帯性植物であるガルシニア(Garcinia cambogia)、ハイビスカス(Hibiscus subdariffa Linn.)に主に含まれる有機酸である。HCAには4種の光学異性体(2S,3S)、(2R,3R)、(2S,3R)、(2R,3S)型が存在する。G. cambogiaには(2S,3S) -HCAが、H.
山田, 靖宙, 山田, 隆志, 飛田, 浩之, 41159, 41161, 41160   +5 more
core  

Efficacy of a dietary supplement derived from five edible plants on telomere length in Thai adults: A randomized, double‐blind, placebo‐controlled trial

Food Science &Nutrition, Volume 12, Issue 3, Page 1592-1604, March 2024.
The research suggests that consuming a dietary supplement (Mylife/Mylife100®), which includes black sesame seeds, guava fruit, mangosteen aril, pennywort leaves, and soy protein, for 8 weeks has a positive impact on cellular aging by lengthening telomeres possible through their antioxidant capacities.
Kemika Praengam, Siriporn Tuntipopipat, Chawanphat Muangnoi, Chatdao Jangwangkorn, Olan Piamkulvanich   +4 more
wiley   +1 more source

Isolation and quantification of hydroxycitric acid from batuan [Garcinia Binucao (Blanco) Choisy] fruit

, 2018
Hydroxycitric acid is a compound with anti-obesity property which is predominant in Garcinia cambogia. In the Philippines, another species, Garcinia binucao, locally known as batuan, is an indigenous fruit used as a souring agent.This study was conducted
Part Time Mohd Zulhimi bin Zolkefali
core  

Multifunctionalized and Dual‐Crosslinked Hydrogel Promotes Inflammation Resolution and Bone Regeneration via NLRP3 Inhibition in Periodontitis

Small Structures, Volume 5, Issue 3, March 2024.
The multifunctionalized hydrogel pGM/cPL@NI with reinforced strength orchestrates functions of antibacteria, reactive oxygen species scavenging, immunomodulation, and osteogenesis promotion. Importantly, the correlation between Porphyromonas gingivalis‐induced NLRP3 inflammasome activation and periodontitis is highlighted, which is effectively blocked ...
Yuyao Liu, Jiayin Yan, Luxian Chen, Yuwei Liao, Lijia Huang, Jiali Tan   +5 more
wiley   +1 more source