High-efficiency production of 5-hydroxyectoine using metabolically engineered Corynebacterium glutamicum [PDF]
Background: Extremolytes enable microbes to withstand even the most extreme conditions in nature. Due to their unique protective properties, the small organic molecules, more and more, become high-value active ingredients for the cosmetics and the ...
Becker, Judith +6 more
core +11 more sources
Microbial production of ectoine and hydroxyectoine as high-value chemicals [PDF]
Ectoine and hydroxyectoine as typical representatives of compatible solutes are not only essential for extremophiles to survive in extreme environments, but also widely used in cosmetic and medical industries.
Yanning Zheng
exaly +6 more sources
New insights into hydroxyectoine synthesis and its transcriptional regulation in the broad‐salt growing halophilic bacterium Chromohalobacter salexigens [PDF]
Summary Elucidating the mechanisms controlling the synthesis of hydroxyectoine is important to design novel genetic engineering strategies for optimizing the production of this biotechnologically relevant compatible solute.
Montserrat Argandoña +4 more
doaj +3 more sources
The MocR/GabR Ectoine and Hydroxyectoine Catabolism Regulator EnuR: Inducer and DNA Binding [PDF]
The compatible solutes ectoine and 5-hydroxyectoine are widely synthesized by bacteria as osmostress protectants. These nitrogen-rich tetrahydropyrimidines can also be exploited as nutrients by microorganisms. Many ectoine/5-hydroxyectoine catabolic gene
Lucas Hermann +9 more
doaj +6 more sources
Glass-forming property of hydroxyectoine is the cause of its superior function as a desiccation protectant [PDF]
We were able to demonstrate that hydroxyectoine, in contrast to ectoine, is a good glass-forming compound. Fourier transform infrared (FTIR) and spin label electron spin resonance (ESR) studies of dry ectoine and hydroxyectoine have shown that the ...
Erwin Arno Galinski +4 more
exaly +6 more sources
Enrichment of halotolerant hydrogen-oxidizing bacteria and production of high-value-added chemical hydroxyectoine using a hybrid biological–inorganic system [PDF]
Hybrid biological–inorganic (HBI) systems show great promise as CO2 conversion platforms combining CO2 fixation by hydrogen-oxidizing bacteria (HOB) with water splitting.
Xiang Feng +9 more
doaj +2 more sources
Stability of Lysozyme in Aqueous Extremolyte Solutions during Heat Shock and Accelerated Thermal Conditions [PDF]
The purpose of this study was to investigate the stability of lysozyme in aqueous solutions in the presence of various extremolytes (betaine, hydroxyectoine, trehalose, ectoine, and firoin) under different stress conditions.
Avanti, Christina +4 more
core +6 more sources
Ectoine and Hydroxyectoine from Halophilic Bacteria Isolated from Traditional Solar Saltern at Pejarakan Village, Buleleng Regency, Bali [PDF]
The increased use of ectoine and hydroxyectoine in cosmetics and pharmaceuticals has led to the increasing demand for these bioactive compounds. This study aims to investigate the production of ectoine and hydroxyectoine by halophilic bacteria isolated ...
I Nyoman Tika +2 more
core +4 more sources
Quantitative RNA-seq Analysis Unveils Osmotic and Thermal Adaptation Mechanisms Relevant for Ectoine Production in Chromohalobacter salexigens [PDF]
Quantitative RNA sequencing (RNA-seq) and the complementary phenotypic assays were implemented to investigate the transcriptional responses of Chromohalobacter salexigens to osmotic and heat stress.
Carmen Vargas +6 more
core +4 more sources
Screening of Moderately Halophilic Bacteria Producing Ectoine Resulting in the Selection of Virgibacillus salarius BHTA19 [PDF]
Research background. Ectoine is a desirable molecule with high application potential, particularly in the cosmetics and pharmaceutical industries. The current production method uses microorganisms that require high salinity.
Martyna Leszczewicz +4 more
doaj +2 more sources

