Journal of Advanced Research, 2019 Gram-negative bacterial endophytes have attracted research interest caused by their advantageous over epiphytic bacteria in plant nutrition and protection. However, research on these typically Gram-negative endophytes has deficiencies concerning the role
Mauricio Cruz Barrera +2 more
exaly +5 more sources
Rational engineering of Halomonas salifodinae to enhance hydroxyectoine production under lower-salt conditions [PDF]
Applied Microbiology and BiotechnologyAbstract Hydroxyectoine is an important compatible solute that holds potential for development into a high-value chemical with broad applications. However, the traditional high-salt fermentation for hydroxyectoine production presents challenges in treating the high-salt wastewater.
Yanning Zheng, Yan Zeng, Hua Xiang
exaly +4 more sources
Temperature- and salinity-decoupled overproduction of hydroxyectoine by chromohalobacter salexigens [PDF]
Applied and Environmental Microbiology, 2012 Hydroxyectoine overproduction by the natural producer Chromohalobacter salexigens is presented in this study. Genetically engineered strains were constructed that at low salinity coexpressed, in a vector derived from a native plasmid, the ectoine (ectABC)
Argandoña Bertrán, Montserrat +4 more
core +6 more sources
Involvement of EupR, a response regulator of the NarL/FixJ family, in the control of the uptake of the compatible solutes ectoines by the halophilic bacterium Chromohalobacter salexigens [PDF]
BMC Microbiology, 2010 Background Osmosensing and associated signal transduction pathways have not yet been described in obligately halophilic bacteria. Chromohalobacter salexigens is a halophilic bacterium with a broad range of salt tolerance.
Javier Rodríguez-Moya +6 more
core +7 more sources
Harnessing Biogas into High-Value Chemicals: The Role of Algal–Methanotrophic Co-Cultures [PDF]
Marine DrugsThe conversion of biogas into high-value chemicals for pharmaceutical, cosmetic, and nutraceutical markets offers an attractive alternative to conventional fossil-based production routes, enabling circular value chains with significant socio-economic ...
Rebecca Serna-García +4 more
doaj +2 more sources
Determination of the extremolyte ectoine in plasma and a pharmacokinetic study in rats by a validated and BAGI-evaluated UPLC-MS/MS method [PDF]
BMC ChemistryEctoine (ECT) has recently gained considerable interest in the healthcare sector due to its promising therapeutic benefits in a variety of human disorders.
Mahmoud Rabee +2 more
doaj +2 more sources
Transcriptomic analysis of chloride tolerance in Leptospirillum ferriphilum DSM 14647 adapted to NaCl. [PDF]
PLoS ONE, 2022 Chloride ions are toxic for most acidophilic microorganisms. In this study, the chloride tolerance mechanisms in the acidophilic iron-oxidizing bacterium Leptospirillum ferriphilum DSM 14647 adapted to 180 mM NaCl were investigated by a transcriptomic ...
Javier Rivera-Araya +4 more
doaj +2 more sources
Establishment of an efficient one-step enzymatic synthesis of cyclic-2,3-diphosphoglycerate [PDF]
Frontiers in MicrobiologyExtremolytes – unique compatible solutes produced by extremophiles - protect biological structures like membranes, proteins, and DNA under extreme conditions, including extremes of temperature and osmotic stress.
Christina Stracke +13 more
doaj +2 more sources
Overexpression of Scr1 protein induces strong changes in the transcriptome and metabolome of Streptomyces coelicolor that affect antibiotic production [PDF]
Microbial Cell FactoriesBackground Xenobiotic response element (XRE) regulator proteins play an important role in gene regulation in Streptomyces. In these bacteria, they are often encoded together with a small protein containing a DUF397 domain.
Carolina Riascos +5 more
doaj +2 more sources
BIOSYNTHESIS AND THE POSSIBILITY OF USING ECTOINE AND HYDROXYECTOINE IN HEALTH CARE [PDF]
Postępy Mikrobiologii, 2019 Abstract The global production of L-amino acids is largely based on microbiological synthesis. The largest bioproduction concerns L-glutamic acid (1.5 million tons per year), and L-lysine (850,000 tons per year). Among other amino acids, ectoine and hydroxyectoine are mentioned in the growing demand.
Weronika Goraj +2 more
doaj +2 more sources