Osmoadaptation mechanisms in prokaryotes: distribution of compatible solutes [PDF]
, 2008 Microorganisms respond to osmotic stress mostly by accumulating compatible solutes, either by uptake from the medium or by de novo synthesis. These osmotically activ molecules preserve the positive turgor pressure required for cell division.
Milton da Costa, Nuno Empadinhas
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Bioactivity profiling of the extremolyte ectoine as a promising protectant and its heterologous production. [PDF]
3 Biotech, 2022 Ma Z +6 more
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, 2019 Changes within the external osmotic potential belong to the most ubiquitous stress factors that microbial cells encounter. A large group of Bacteria, but also a few Archaea and unicellular halophilic Eukarya possess the genetic information to produce the compatible solutes and chemical chaperones ectoine and its derivative 5-hydroxyectoine.
Czech, Laura, Bremer, Erhard (Prof. Dr.)
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Utilization and accumulation of compatible solutes in Halomonas pacifica: a species of moderately halophilic bacteria isolated from a saline lake in South Libya. [PDF]
Access Microbiol, 2022 Abosamaha A, Williamson MP, Gilmour DJ.
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Hydroxyectoine Metabolism in Halomonas elongata [PDF]
, 2013 The marine Gram-negative bacterium Halomonas elongata is known to produce hydroxyectoine (8), a molecule that is valuable because of its broad spectrum of potential industrial applications. However, the widespread use of hydroxyectoine has been partially
Correa Acosta, Jhonny Edmith
core
Unexplored Excipients in Biotherapeutic Formulations: Natural Osmolytes as Potential Stabilizers Against Thermally Induced Aggregation of IgG1 Biotherapeutics. [PDF]
AAPS PharmSciTech, 2021 Bhojane PP +3 more
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Enhanced production of ectoine from methane using metabolically engineered Methylomicrobium alcaliphilum 20Z. [PDF]
Biotechnol Biofuels Bioprod, 2022 Cho S +5 more
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Synthese und physiologische Funktion der chemischen Chaperone Ectoin und Hydroxyectoin
, 2012 Eine unter Bakterien weit verbreitete Anpassungsstrategie an hyperosmotische Umgebungsbedingungen ist die Aufnahme oder die Synthese von osmotisch wirksamen Substanzen, die sogenannten kompatiblen Solute. In dieser Arbeit wurden hauptsächlich Aspekte aus dem Bereich der Synthese von den sogenannten kompatiblen Soluten
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Editorial: Microbiomics in food security: paradigm shift in omics. [PDF]
Front Microbiol, 2023 Vaishnav A, Jain S, Choudhary DK.
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Integrative multi-omics reveals the metabolic and functional diversity of microbiomes in the gut microenvironment. [PDF]
Front Microbiol, 2023 Qiu S +6 more
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