Due to the drastic shortage of organ donors, clinicians are increasingly considering the use of deceased after cardiac death donors (DCD). Compatible solutes like Ectoine and Hydroxyectoine are produced by extremophilic bacteria as a cell protectant to survive in harsh environments.
Pramod, Kadaba Srinivasan +7 more
openaire +2 more sources
Role of N γ-Acetyldiaminobutyrate as an Enzyme Stabilizer and an Intermediate in the Biosynthesis of Hydroxyectoine [PDF]
ABSTRACT Strain CHR63 is a salt-sensitive mutant of the moderately halophilic wild-type strain Halomonas elongata DSM 3043 that is affected in the ectoine synthase gene ( ectC ). This strain accumulates large amounts of N γ-acetyldiaminobutyrate (NADA), the ...
Nieto Gutiérrez, Joaquín José +5 more
openaire +4 more sources
Osmotically Induced Synthesis of the Compatible Solute Hydroxyectoine Is Mediated by an Evolutionarily Conserved Ectoine Hydroxylase [PDF]
By using natural abundance (13)C NMR spectroscopy, we investigated the types of compatible solutes synthesized in a variety of Bacilli under high salinity growth conditions. Glutamate, proline, and ectoine were the dominant compatible solutes synthesized by the various Bacillus species.
Jan, Bursy +3 more
openaire +2 more sources
Heterologous ectoine production in : By-passing the metabolic bottle-neck [PDF]
Peer ...
Erwin A Galinski +2 more
core +2 more sources
Properties of osmolytes that help protect biological molecules from stress and preserve their functions impose significant importance to finding new organisms with different osmolyte accumulation strategies. To this end, the moderately halophilic Halomonas sp. AAD12 has been characterized for its adaptation to stress conditions with particular emphasis
Öztürk HU +5 more
openaire +4 more sources
Deciphering ocean carbon in a changing world [PDF]
Author Posting. © The Author(s), 2016. This is the author's version of the work. It is posted here for personal use, not for redistribution. The definitive version was published in Proceedings of the National Academy of Sciences of the United States of
Aluwihare, Lihini I. +16 more
core +1 more source
The key enzyme for mannosylglyceramide synthesis in Rhodothermus marinus [PDF]
Mestrado em Biologia AplicadaNa presença de elevadas concentrações de sal no meio de cultura a bactéria halotermofílica Rhodothermus marinus acumula no interior das células compostos orgânicos de baixo peso molecular designados solutos compatíveis ...
Ferreira, Ana Catarina Morouço
core
Charakterisierung der molekularen Determinanten zur hochaffinen Bindung der kompatiblen Soluten Glycin Betain, Prolin Betain, Ectoin und Hydroxyectoin durch Substratbindeproteine von bakteriellen ABC-Transportern [PDF]
Die Akkumulation von kompatiblen Soluten ist ein weit verbreiteter Schutzmechanismus gegen variierende Umweltbedingungen und wird in vielen Spezies der Bacteria und Archaea verwendet.
Bremer, Erhard (Prof. Dr.) +1 more
core +1 more source
Comparative functional genomics approach for the annotation of proteins in Unclassified Halophilic archaeon DL31 [PDF]
The structure, function and sub-cellular location prediction for the unknown proteins from Unclassified Halophilic archaeon DL31 were carried out for characterization of the proteins in their respective families.
E Nakkeeran +2 more
core +1 more source
New Halonotius Species Provide Genomics-Based Insights Into Cobalamin Synthesis in Haloarchaea [PDF]
Hypersaline aquatic and terrestrial ecosystems display a cosmopolitan distribution. These environments teem with microbes and harbor a plethora of prokaryotic lineages that evaded ecological characterization due to the prior inability to cultivate them ...
Andrei, Adrian-Stefan +3 more
core +1 more source

