Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide [PDF]
, 2010 The association between suicide and G-703T polymorphism of the tryptophan hydroxylase 2 (TPH2), the rate-limiting enzyme in the biosynthesis of the neurotransmitter serotonin, was studied in a sample of 291 suicide victims and 280 healthy subjects of ...
Bakula, Mirko +6 more
core +1 more source
Cancer Medicine, Volume 14, Issue 6, March 2025.ABSTRACT Background Differentiated thyroid cancer (DTC) is the primary subtype of thyroid cancer. Timely diagnosis and intervention are crucial for improving prognosis and survival. However, the effectiveness of existing serum markers is limited, necessitating the discovery of new biomarkers.
Qiang Miao +6 more
wiley +1 more source
Mycoplasma pneumoniae associated opsoclonus-myoclonus syndrome in three cases [PDF]
, 2018 Opsoclonus-myoclonus syndrome (OMS) is a rare acquired movement disorder occurring in all age groups, predominantly in infants. Although the exact pathogenesis is still undefined, there is strong evidence for a paraneoplastic or parainfectious immune ...
Aebi, Christoph +4 more
core
Catha edulis chewing effects on treatment of paranoid schizophrenic patients
Neuropsychiatric Disease and Treatment, 2015 Mohamed-I Kotb El-Sayed, Hatem-K Amin Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Ain Helwan, Helwan, Cairo, Egypt Background: The current study’s aim is to evaluate the possible interaction ...
Kotb El-Sayed MI, Amin HK
doaj
JIMD Reports, Volume 66, Issue 2, March 2025.ABSTRACT Phenylketonuria (PKU) is an inborn error of metabolism responsible for an accumulation of phenylalanine, which leads to cognitive and developmental disorders if left untreated. Most studies of adult PKU focus on neuropsychiatric complications, but new questions have been raised about systemic manifestations of PKU in adulthood.
Yann Dos Santos +7 more
wiley +1 more source
LC/ESI-MS analysis of underivatized amino acids and mass spectrum [PDF]
arXiv, 2016 We report the method of LC/ESI-MS analysis of underivatized amino acids with corresponding mass spectrum and fragmentation patterns. Diagnostic product ions determined by mass spectrometry can support the qualitative identification and quantitative estimation of individual amino acids. Therefore, the optimization of chromatographic separation using the
arxiv
Influence of 2,5-Hexanedione, Acrylamide, Tri-O-Tolyl Phosphate, Leptophos and Methylmercury on Endogenous Levels of Tryptophan, Serotonin and 5-Hydroxyindoleacetic Acid and Serotonin Turnover Rates in Rat Brain [PDF]
, 1992 Several industrial and environmental chemicals cause distal and/or central neuropathy among other diverse toxic effects. Spague-Dawley derived rats were fed doses of 2,5-hexanedione, acrylamide, tri-o-tolyl phosphate, leptophos and methylmercury via ...
Farr, Craig H.
core +1 more source
Chronic Activation of Corticotropin-Releasing Factor Type 2 Receptors Reveals a Key Role for 5-HT1A Receptor Responsiveness in Mediating Behavioral and Serotonergic Responses to Stressful Challenge [PDF]
, 2012 BackgroundThe corticotropin-releasing factor type 2 receptor (CRFR2) is suggested to play an important role in aiding recovery from acute stress, but any chronic effects of CRFR2 activation are unknown.
Abrams +100 more
core +1 more source
Correlations of Amino Acids with Secondary Structure Types: Connection with Amino Acid Structure [PDF]
arXiv, 2005 The correlations of primary and secondary structures were analyzed using proteins with known structure from Protein Data Bank. The correlation values of amino acid type and the eight secondary structure types at distant position were calculated for distances between -25 and 25.
arxiv
Synchronous primary papillary breast cancer, medullary thyroid carcinoma and neuroendocrine tumor in postmenopausal woman. [PDF]
, 2016 Multiple endocrine neoplasia are syndromes involving two or more endocrine tissues, often correlated to RET proto-oncogene mutations. We herein present the first reported case of a 57-years-old woman with three synchronous primary cancers of breast ...
DE IULIIS, Francesca +7 more
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