Results 41 to 50 of about 32,751 (204)
Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation
Advanced Science, EarlyView.Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang +4 more
wiley +1 more source
International Journal of Electrochemical Science, 2013 The direct electrochemistry of Hydroxylamine oxidase (HAO) / zinc oxide (Zno) nanoparticles (Nps) /carbon paste electrode (CPE) was studied for design a new biosensor for detect Nitrite (NO2-) and hydroxylamine (NH2OH).
Masoud Mohammadian +8 more
doaj +1 more source
Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors
Advanced Science, EarlyView.This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng +12 more
wiley +1 more source
Tikrit Journal of Pure Science, 2023 This study investigated the condensation reactions between N-(3,4-dimethoxybenzyl)hydroxylamine and N-(4-methylbenzyl)hydroxylamine with glyoxalic acid. The objective was to obtain imine derivatives as the desired target products.
Jihad Haji Mohammed +3 more
doaj +1 more source
Advanced Science, EarlyView.Inspired by Nitrite reductase, a metal–organic framework overlayer is introduced to regulate the interfacial hydration microenvironment on Cu electrodes, enriching hydrated K+ species that act as efficient proton donors. This strategy enables nitrate‐to‐ammonia conversion with near‐unity selectivity at industrial‐level current densities in neutral ...
Yuyin Mao +4 more
wiley +1 more source
Advanced Science, EarlyView.A hierarchically porous AOPIM‐CNT electrode enables uranium harvesting from seawater via adsorption‐promoted electrodeposition. Rapid diffusion and selective adsorption are coupled with electrochemical crystallization and spontaneous detachment, creating a self‐refreshing process that sustains high‐capacity, continuous extraction from ultradilute ...
Zejun Song +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.This study employs a RuV═NH complex with hydrogen‐bonding (HB) sites in the SCS to afford non‐N‐substituted aziridines selectively. Nitrogen‐atom transfer occurs from the RuV═NH complex to alkenes in water to produce aziridine derivatives in high yields.
Tomoya Ishizuka +7 more
wiley +2 more sources
Nature Communications, 2023 Despite the rich coordination chemistry, hydroxylamines are rarely used as ligands for transition metal coordination compounds. This is partially because of the instability of these complexes that undergo decomposition, disproportionation and oxidation ...
Vladislav K. Lesnikov +4 more
doaj +1 more source
Atroposelective Construction of Axially Chiral Tetraarylethenes Via NHC‐Catalyzed Desymmetrization
Advanced Science, EarlyView.We report the first NHC‐catalyzed atroposelective synthesis of axially chiral TAEs via oxidative desymmetrization of prochiral TAE dialdehydes. This catalytic strategy operates under mild conditions and accommodates a broad range of phenolic and nitrogen nucleophiles, delivering diverse axially chiral TAEs in good yields and up to 99% ee.
Yang‐Ze Zheng +6 more
wiley +1 more source
Crystal structure of N-(quinolin-6-yl)hydroxylamine
Acta Crystallographica Section E, 2014 The title compound, C9H8N2O, crystallized with four independent molecules in the asymmetric unit. The four molecules are linked via one O—H...N and two N—H...N hydrogen bonds, forming a tetramer-like unit.
Anuruddha Rajapakse +5 more
doaj +1 more source