ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
Atypical Condensation Domains Guide Discovery and Illuminate Biosynthesis of Myxoglucamides Featuring Vinyl-Substituted, α-Oxidized γ-Amino Acids. [PDF]
Wang T +10 more
europepmc +1 more source
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Characterization of a CYP107 family vitamin D<sub>3</sub> carbon-25 hydroxylase; insights toward vitamin D<sub>3</sub> recognition by a cytochrome P450. [PDF]
Jensen LJ, Estrada DF.
europepmc +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
Cytochrome P450- and Dehydrogenase-Mediated Regiospecific and Stereoselective Formation of β- and γ-Lactones in Drimane-Type Sesquiterpenoid Biosynthesis. [PDF]
Wu M, Wu J, Janzen DJ, Yin WB, Li SM.
europepmc +1 more source
BTID‐functionalized metal‐organic frameworks provide a modular platform for tailoring photocatalytic electronic structures through acceptor‐linker engineering. By correlating band alignment, charge‐transfer characteristics, and reactive oxygen species generation, this review highlights design principles that enable efficient visible‐light‐driven ...
Xin Li +3 more
wiley +1 more source
Bifurcated Fluorotelomer Carboxylic Acid Biotransformation: Enoyl-Hydration versus Hydroxylation Regulated by Redox Conditions. [PDF]
Su B, Chen H, Washington J, Li M.
europepmc +1 more source
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang +6 more
wiley +1 more source
Participation of redox-active residues in polysaccharide monooxygenase catalysis. [PDF]
Batka AE, Bhat A, Rose AJ, Marletta MA.
europepmc +1 more source

