Results 181 to 190 of about 143,720 (300)

Study on Phase I Metabolic Processes and Metabolite Biomarker Identification of Synthetic Cannabinoids 5F-ADB-PINACA and 5F-ADBICA in Human Liver Microsomes and Zebrafish Model. [PDF]

Molecules
Li H, Zheng H, Zhong S, Zhao Y, Lin J, Su H, Qian Z, Wang Y.   +7 more
europepmc   +1 more source

Structural Basis for Trivalent Cross‐Linking of a Patient‐Derived IgE Antibody by the Major Peanut Allergen Ara h 2.0201

Allergy, EarlyView.
Graphical The crystal structure of a major peanut allergen Ara h 2.0201 in a complex with a human‐derived IgE Fab fragment has been determined. The immunocomplex shows the trivalent binding of Fabs, creating a cross‐linked structure effective in the formation of large complexes on the surface of effector cells. Hydroxylation of proline has implications
Tarja Parkkinen, Heidi Heiniluoto, Janne Jänis, Kristiina Takkinen, Juha Rouvinen   +4 more
wiley   +1 more source

Effect of Cytochrome P450 2C9 genetic polymorphism on agomelatine metabolism <i>in vitro</i>. [PDF]

PeerJ
Fang P, Ni J, Shen T, Chen Q, Ye X, Jin J, Dai D, Hu G, Qian J, Cai J, Chen L.   +10 more
europepmc   +1 more source

Tale of two transcription factors: NF-кB and HIF crosstalk [PDF]

, 2013
Bandarra, D., Rocha, S.
core   +1 more source

Enhancing the fastness characteristics of weld‐dyed cotton and recycled nylon 6,6 fabrics via sodium alginate and titanium dioxide

Coloration Technology, EarlyView.
Abstract This study investigates a sustainable dyeing and finishing strategy for recycled nylon 6,6 and organic cotton fabrics dyed with weld. Following meta‐mordant dyeing using alum under Natural Organic Dye Standard (NODS)‐compliant conditions, the fabrics were subjected to functional finishing with titanium dioxide as a multifunctional ...
Recep Karadag, Fatma Zehra Engin Sagirli, Abdulkadir Pars   +2 more
wiley   +1 more source

Oxidative Peptide Backbone Cleavage by a HEXXH Enzyme during RiPP Biosynthesis. [PDF]

J Am Chem Soc
Ouyang Y, Yu Y, Zhu L, Nguyen DT, van der Donk WA.   +4 more
europepmc   +1 more source

Dissociation of stimulatory effects of cortocotrophin on adrenal corticosterone and protein synthesis following hypophysectomy [PDF]

, 1968
Kluge, F., Scriba, Peter Christian
core  

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

The FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou, Christina Arseni, Kreon Koukoulas, Martina Samiotaki, George Panayotou, George Simos, Ilias Mylonis   +6 more
wiley   +1 more source

Comprehensive metabolic profiling of the new designer stimulant MDPiHP-in vitro and in vivo identification of potential biomarkers for detection in human samples. [PDF]

Anal Bioanal Chem
Balloni A, Kutzler J, Basile G, Busardò FP, Carlier J, Auwärter V.   +5 more
europepmc   +1 more source

Rethinking the role of HIF in hepatocellular carcinoma

The FEBS Journal, EarlyView.
Tumor hypoxia is a hallmark of cancer driving disease, in part through activation of hypoxia‐inducible factors (HIFs). While HIF‐1α is classically understood as a hypoxia‐responsive transcription factor, its role under normoxic conditions in cells is less clear.
Niall S. Kenneth, Michael Batie, Sonia Rocha   +2 more
wiley   +1 more source