Results 11 to 20 of about 95,661 (297)
A computational mechanistic study of CH hydroxylation with mononuclear copper-oxygen complexes [PDF]
, 2022 We present a computational study of methane hydroxylation by oxygen-bound monocopper complexes with the twin goals of resolving the active site identity and preferred mechanism of CH activation.
Zhenzhuo, Lan +5 more
core +2 more sources
The hydroxylation of ?5-androstenes by Cephalosporium aphidicola
, 1998 Whereas the major hydroxylation product of 3?-hydroxy-5?-androstan-17-one by Cephalosporium aphidicola is the 11?-alcohol, the presence of a ?5-double bond in the substrate leads to non-stereospecific allylic hydroxylation at C–7.
Christy Hunter (17160439) +2 more
core +4 more sources
Radical–Anion Coupling Through Reagent Design: Hydroxylation of Aryl Halides [PDF]
, 2021 The design and development of an oxime-based hydroxylation reagent, which can chemoselectively convert aryl halides (X = F, Cl, Br, I) into phenols under operationally simple, transition-metal-free conditions is described.
Adrian C., Whitwood +5 more
core +2 more sources
, 1998 Hydroxylation of pregna-4-en-3-ones at C-11? by the fungus Cephalosporium aphidicola is shown to be affected by the nature of the pregnane side chain whilst hydroxylation at C-6? is unaffected.
Christy Hunter (17160439) +1 more
core +6 more sources
Specificity Determinants of CYP1B1 Estradiol Hydroxylation [PDF]
, 2013 Cytochrome P450 (P450)-catalyzed oxidation of the aromatic ring of estradiol can result in 2- or 4-hydroxylation. Which of these products is formed is biologically important, as the 4-hydroxylated metabolite is carcinogenic, whereas the 2-hydrox-ylated ...
Nishida, Clinton R +7 more
core +1 more source
A New Stilbene Glucoside from Biotransformation-Guided Purification of Chinese Herb Ha-Soo-Oh
Plants, 2022 Ha-Soo-Oh is a traditional Chinese medicine prepared from the roots of Polygonum multiflorum Thunb. The herb extract has been widely used in Asian countries as a tonic agent and nutritional supplement for centuries. To identify new bioactive compounds in
Jiumn-Yih Wu +4 more
doaj +1 more source
Fatty acid hydroxylation by CYP168A1.
, 2022 Fatty acid hydroxylation by CYP168A1.
Diane E. Kelly (7585250) +7 more
core +1 more source
Peroxide-Mediated Oxygenation of Organic Compounds by Fungal Peroxygenases
Antioxidants, 2022 Unspecific peroxygenases (UPOs), whose sequences can be found in the genomes of thousands of filamentous fungi, many yeasts and certain fungus-like protists, are fascinating biocatalysts that transfer peroxide-borne oxygen (from H2O2 or R-OOH) with high ...
Martin Hofrichter +6 more
doaj +1 more source
Efficient regio- and stereoselective access to novel fluorinated β-aminocyclohexanecarboxylates
Beilstein Journal of Organic Chemistry, 2013 A regio- and stereoselective method has been developed for the synthesis of novel fluorinated 2-aminocyclohexanecarboxylic acid derivatives with the fluorine attached to position 4 of the ring.
Loránd Kiss +4 more
doaj +1 more source
Molecules, 2019 The inhibition of recombinant CpLIP2 lipase/acyltransferase from Candida parapsiolosis was considered a key model for novel antifungal drug discovery and a potential therapeutic target for candidiasis. Lipases have identified recently as potent virulence
Ruba Nasri +6 more
doaj +1 more source